Results 121 to 130 of about 8,859,528 (311)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The use of biomarkers in fresh meat and dairy products to identify the feeding regime in ruminants: a review

open access: yesCogent Food & Agriculture
Advances in foodomics have demonstrated the feasibility of detecting specific molecules, known as ‘foodomes’, that can serve as biomarkers in fresh meat and dairy products to identify the origin of feeding foods.
Alberto Horcada   +3 more
doaj   +1 more source

Geschmack- und gesundheitsrelevante Qualität von ökologisch angbauten Äpfeln: Eine 3jährige Feldvergleichsstudie mit standard- und ganzheitlichen Untersuchungsmethoden [PDF]

open access: yes, 2004
In a 3 years lasting field study with the ‘Golden Delicious’ cultivar, we compared fruits of 5 pairs of organic/integrated fruit farms. The orchards were similar in microclimate, soil conditions and planting system.
Graf, Ursula   +3 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Performances of full cross-validation partial least squares regression models developed using Raman spectral data for the prediction of bull beef sensory attributes

open access: yesData in Brief, 2018
The data presented in this article are related to the research article entitled “Application of Raman spectroscopy and chemometric techniques to assess sensory characteristics of young dairy bull beef” [1].
Ming Zhao   +5 more
doaj   +1 more source

Effect of locally available spices on the organoleptic and storage periods of Heterotis niloticus [PDF]

open access: yes, 2005
Investigation were carried out on the effect of some locally available species in the enhancement of the organoleptic quality and the storage periods of smoked Heterotis niloticus using Pprosopis africana as common smoke sources.
Ogbe, F.G., Okpale, E.O., Tiamiyu, L.O.
core  

Chemical and Sensory Quality Preservation in Coated Almonds with the Addition of Antioxidants.

open access: yesJournal of Food Science, 2016
Almonds provide many benefits such as preventing heart disease due to their high content of oleic fatty acid-rich oil and other important nutrients. However, they are susceptible to oxidation reactions causing rancidity during storage.
Mariana Larrauri   +5 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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