Results 91 to 100 of about 119,051 (295)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Short-term memory effects of an auditory biofeedback on isometric force control: Is there a differential effect as a function of transition trials?

open access: yes, 2011
The aim of the present study was to investigate memory effects, force accuracy, and variability during constant isometric force at different force levels, using auditory biofeedback.
Cuisinier, Rémy   +4 more
core   +3 more sources

Embodied Cognition and Perception: Dewey, Science and Skepticism [PDF]

open access: yes, 2017
This article examines how Modern theories of mind remain even in some materialistic and hence ontologically anti-dualistic views; and shows how Dewey, anticipating Merleau-Ponty and 4E cognitive scientists, repudiates these theories.
Matthew, Crippen
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

3D Ultrastructure of the Cochlear Outer Hair Cell Lateral Wall Revealed By Electron Tomography. [PDF]

open access: yes, 2019
Outer Hair Cells (OHCs) in the mammalian cochlea display a unique type of voltage-induced mechanical movement termed electromotility, which amplifies auditory signals and contributes to the sensitivity and frequency selectivity of mammalian hearing ...
Auer, Manfred   +6 more
core   +3 more sources

Sensory Substitution and Echolocation

open access: yes, 2023
Abstract Sensory substitution is a complicated technique that helps blind people gain real-time information about the layout of the scene in front of them. Echolocation is an equally complicated technique of emitting sounds to map the terrain of one’s surroundings.
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Accessibility and adaptability of learning objects: responding to metadata, learning patterns and profiles of needs and preferences [PDF]

open access: yes, 2006
The case for learning patterns as a design method for accessible and adaptable learning objects is explored. Patterns and templates for the design of learning objects can be derived from successful existing learning resources.
Gkatzidou, Stavroula   +3 more
core   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

EFFECT OF PARTIAL REPLACEMENT OF WHEAT AND RICE FLOUR BY MODIFIED STARCH ON CAKE AND BISCUIT QUALITATIVE AND SENSORY PROPERTIES

open access: yesThe Iraqi Journal of Agricultural science
This study was aimed to investigate the effect of substituting different proportions (10%, 20%, 30%) of wheat flour and Amber rice with enzymatically modified starch  on qualitative and sensory characteristics of biscuits and cupcakes.
Zina HusseinAbdel Mahdi   +1 more
doaj   +1 more source

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