Results 191 to 200 of about 885,062 (268)

Whisker pad stimulation with different frequencies reveals non-uniform modulation of functional MRI signal across sensory systems in awake rats. [PDF]

Cereb Cortex
Paasonen J, Valjakka JS, Salo RA, Paasonen E, Tanila H, Michaeli S, Mangia S, Gröhn O.   +7 more
europepmc   +1 more source

Auditory and tactile frequency representations are co-embedded in modality-defined cortical sensory systems. [PDF]

Neuroimage, 2020
Rahman MS, Barnes KA, Crommett LE, Tommerdahl M, Yau JM.   +4 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Through an animal's eye: the implications of diverse sensory systems in scientific experimentation. [PDF]

Proc Biol Sci
Brebner JS, Loconsole M, Hanley D, Vasas V.   +3 more
europepmc   +1 more source

Effects of neonatal isoflurane anesthesia exposure on learning-specific and sensory systems in adults. [PDF]

Sci Rep, 2020
Aksenov DP, Venkatasubramanian PN, Miller MJ, Dixon CJ, Li L, Wyrwicz AM.   +5 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Contributions and future potential of animal models for geroscience research on sensory systems. [PDF]

Geroscience
Fernandes AG, Poirier AC, Veilleux CC, Melin AD.   +3 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Body-Integrated Ultrasensitive All-Textile Pressure Sensors for Skin-Inspired Artificial Sensory Systems. [PDF]

Small Sci
Wang B, Shi Y, Li H, Hua Q, Ji K, Dong Z, Cui Z, Huang T, Chen Z, Wei R, Hu W, Shen G.   +11 more
europepmc   +1 more source