Results 81 to 90 of about 41,652 (228)

Switching PD‐1 to BRAF + MEK inhibition improves recurrence‐free survival in patients receiving a second course of adjuvant melanoma therapy

Journal of the European Academy of Dermatology and Venereology, EarlyView.
66 patients from 22 centers received adjuvant treatment after relapse under or after previous adjuvant therapy with BRAF + MEK or PD‐1. Data highlight a significant benefit when switching from PD‐1 to BRAF + MEK adjuvant therapy compared to a switch from BRAF + MEK to PD‐1 adjuvant regimens.
Katharina Schumann, Kai Christian Klespe, Cornelia Mauch, Carmen Loquai, Ulrike Schultheis, Sevil Börger, Alexander Thiem, Steffen Emmert, Magdalena Hoellwerth, Peter Kölblinger, Van Anh Nguyen, Marina Wanner, Erika Richtig, Wiebke K. Peitsch, Wolfgang Harth, Veronika Zenderowski, Andreas Dominik Braun, Miriam Mengoni, Reinhard Dummer, Johanna Mangana, Lara Valeska Maul, Frank Meiß, Klemens Rappersberger, Oana Diana Persa, Tilo Biedermann, Christian Posch   +25 more
wiley   +1 more source

Non‐invasive characterization of melanoma depth at single‐cell resolution

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Non‐invasive determination of Breslow depth would be beneficial for the clinical management of melanoma. We demonstrate that RSOM can achieve non‐invasive imaging of single melanocytes up to several millimetres in tissue. A pilot clinical study showed a high degree of correlation between RSOM and the standard for Breslow depth determination.
Juan Aguirre, Christine Gasteiger, Benedikt Hindelang, Markus Seeger, Andrei Bereznhoi, Ina Weidenfeld, Ulf Darsow, Andre C. Stiel, Susanne Annette Steimle‐Grauer, Christian Posch, Tilo Biedermann, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Inverse Regulation of TLR4 and PD‐L1 Shapes the Inflammatory Tumor Microenvironment in Oral Squamous Cell Carcinomas

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background The interactions between malignant cells and immune cells within the tumor microenvironment (TME) significantly influence cancer development and progression. This study aimed to analyze and correlate the expression of TLR4 and PD‐L1 with the immune response, clinical characteristics, and prognosis of oral squamous cell carcinomas ...
Camila Alves Ferri, Giuseppe Pannone, Maria Carmela Pedicillo, Giorgio Mori, Ilenia Sara De Stefano, Francesco Angelillis, Raffaele Barile, Roberta Seccia, Silvana Papagerakis, Angela Santoro, Gian Franco Zannoni, Gabriella Aquino, Margherita Cerrone, Monica Cantile, Vito Rodolico, Giuseppina Campisi, Renato Franco, Francesco Miele, Rosanna Zamparese, Francesco Longo, Lorenzo Lo Muzio, Fernanda Visioli   +21 more
wiley   +1 more source

Influence of sentinel lymph node biopsy on the prognosis of acral melanoma patients. [PDF]

An Bras Dermatol
Francischetto T, Falcão AC, Neves AS, Lira AB, Moura RF, Moura TSOF, Santos JAI, Lima ABC, Lessa MAO, Santos JB, Albuquerque AF, Pinheiro VPDSF.   +11 more
europepmc   +1 more source

Sentinel Lymph Node Biopsy

Actas Dermo-Sifiliográficas (English Edition), 2019
openaire   +2 more sources

Metabolic Heterogeneity Confers Differences in the Tumor Microenvironment of Aggressive Types of Melanomas

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Melanoma affects skin and mucosa and can be particularly aggressive when the lesion is an advanced cutaneous tumor or located in the sinonasal or oral mucosa. Reprogramming of energy metabolism has been defined as a hallmark of cancer; so this study aimed to verify the expression of proteins related to metabolism and cellular ...
Juliana de Souza do Nascimento, João Figueira Scarini, Erika Said Abu Egal, Marcelo Brum Corrêa, Rodrigo Ribas Dias dos Reis, Luciana Schultz Amorim, Rachel Martins Marinho Robim, Clóvis Antônio Lopes Pinto, Patricia Maria Peresi, Ana Lucia Noronha Francisco, Felipe Paiva Fonseca, Luiz Paulo Kowalski, Román Carlos, Fernanda Viviane Mariano, Albina Altemani   +14 more
wiley   +1 more source

Sentinel lymph node biopsy in malignant melanoma: a series of 100 consecutive patients

, 2000
Shehan Hettiaratchy, Norbert Kang, Gregory O’Toole, B.W.E.M. Powell, R. Allan, Martin Cook   +5 more
openalex   +1 more source

Omitting sentinel lymph node biopsy in early breast cancer: too bold or the future? [PDF]

Transl Breast Cancer Res
Zhao J, Zhou Z, Zhang W, Chen K.
europepmc   +1 more source

Preoperative Staging in Oral Cavity Cancer: Nationwide Practice and Concordance With Pathology

Oral Diseases, EarlyView.
ABSTRACT Objectives The clarity of TNM‐classification for oral cancer has a direct impact on healthcare resource allocation, treatment decisions, morbidity, and clinical outcomes. However, possible TNM ambiguity between hospitals exists due to the broad range of available diagnostics.
Hanneke Doremiek van Oorschot, Julie Maria Leonardus Sijmons, Jose Angelito Hardillo, Robert Jan Baatenburg de Jong, Dutch Head and Neck Audit ‐ Oral Cavity Collaborator Group, Robert J. J. van Es, Guido B. van den Broek, Robert P. Takes, Gyorgy B. Halmos, Dominique V. C. de Jel, Jan‐Jaap Hendrickx, Richard Dirven, Martin Lacko, Lauretta A. A. Vaassen, Alexander J. M. van Bemmel, Reinoud Klijn, Marjolijn A. E. Oomens, Hossein Ghaeminia, Leonora Q. Schwandt, Christiaan A. Krabbe, Annemarie Vesseur, Rolf Bun, Thomas J. W. Klein Nulent, Jeroen C. Jansen   +23 more
wiley   +1 more source

Sentinel Lymph Nodes Show Profound Downregulation of Antigen-Presenting Cells of the Paracortex: Implications for Tumor Biology and Treatment [PDF]

, 2001
Alistair J. Cochran, Donald L. Morton, Stacey L. Stern, Ana Maria Arruda Lana, Richard Essner, Duan‐Ren Wen   +5 more
openalex   +1 more source