Results 121 to 130 of about 166,676,583 (294)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Sparse separation of sources in 3D soundscapes [PDF]

open access: yes, 2010
A novel blind source separation algorithm applicable to extracting sources from within 3D soundscapes is presented. The algorithm is based on constructing a binary mask based on directional information. The validity of filtering using binary masked based
Bunting, Oliver
core  

Vadim Kuznetsov. Informal Biography by Eyes of His First Adviser

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2007
The paper is dedicated to the memory of prominent theoretical physicist and mathematician Dr. Vadim Kuznetsov who worked, in particular, in the fields of the nonlinear dynamics, separation of variables, integrability theory, special functions.
Igor V. Komarov
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Application of method of separation of variables for analyzing floating breakwaters

open access: yesنشریه مهندسی دریا, 2016
In this article, a rectangular cross section breakwater in water of finite depth and infinite domain is studied using the separation of the variables method in regular, sinusoidal waves.
Esmaeel Masoodi, hamid Zeraatgar
doaj  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Separation of Variables in the Semistable Range [PDF]

open access: yes, 2019
In this paper, we give an alternative proof of separation of variables for scalar-valued polynomials $P:(\mathbb R^m)^k\to\mathbb C$ in the semistable range $m\geq 2k-1$ for the symmetry given by the orthogonal group $O(m)$. It turns out that uniqueness of the decomposition of polynomials into spherical harmonics is equivalent to irreducibility of ...
openaire   +2 more sources

Construction of a solution to a boundary-value problem a third-order nonhomogeneous equation using Green's function

open access: yesСовременная математика: Фундаментальные направления
In this paper, we consider the third boundary-value problem for a third-order nonhomogeneous equation with multiple characteristics in three-dimensional space.
Yu. P. Apakov, A. A. Khamitov
doaj   +1 more source

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