Results 101 to 110 of about 166,676,583 (294)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Testing for Separation in Agricultural Household Models and Unobservable Individual Effects: A Note [PDF]

open access: yes
When market structure is complete, factor demands by households will be independent of their characteristics, and households will take their production decisions as if they were profit-maximizing firms.
Béatrice D'HOMBRES, Jean-Louis ARCAND
core  

Numerical comparison of pipe-column-separation models [PDF]

open access: yes, 1994
Results comparing six column-separation numerical models for simulating localized vapor cavities and distributed vaporous cavitation in pipelines are presented.
Bergant, A., Simpson, A.
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Separation of polyphenols using porous polyamide resin and assessment of mechanism of retention

open access: yes, 2011
A porous polyamide resin is shown to possess hydrogen bond acceptor properties suitable for the separation of polyphenolic solutes such as phenolic acids, flavonols and flavonoids.
Janson, Jan-Christer   +13 more
core   +1 more source

Implementing parallel elliptic solver on a Beowulf cluster

open access: yesElectronic Journal of Differential Equations, 1999
In a recent paper cite{zara} a parallel direct solver for the linear systems arising from elliptic partial differential equations has been proposed. The aim of this note is to present the initial evaluation of the performance characteristics of this ...
Marcin Paprzycki   +2 more
doaj  

On Darboux's Approach to R-Separability of Variables

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2011
We discuss the problem of R-separability (separability of variables with a factor R) in the stationary Schrödinger equation on n-dimensional Riemann space.
Adam Szereszewski, Antoni Sym
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

An interesting case of variables separation

open access: yesApplied Mathematics Letters, 2000
There is an application of holomorphic expansions \[ W= \sum^\infty_{|n|= 0}\overline z^n W_n(z)\tag{HE} \] and connected results to construct explicit solution for linear partial differential equation (PDE) with constant coefficients, as for instance heat, wave or Laplace equations.
openaire   +3 more sources

Recent advances in lipidomics for disease research

open access: yes, 2016
Lipidomics is an important branch of metabolomics, which aims at the detailed analysis of lipid species and their multiple roles in the living system.
Shen, Sensen   +11 more
core   +1 more source

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