Results 91 to 100 of about 1,287,809 (281)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Separation of variables for the quantum relativistic Toda lattices
, 1994 We consider quantum analogs of the relativistic Toda lattices and give new $2\times 2$ $L$-operators for these models. Making use of the variable separation the spectral problem for the quantum integrals of motion is reduced to solving one-dimensional ...
Kuznetsov, V. B., Tsiganov, A. V.
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A mathematical model of heat transfer in apparatus of air cooling of oil
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2012 In this paper the boundary value problem describing the process of unsteady heat transfer in apparatus of air cooling of oil is formulated and solved. Different modes of operation of such heat exchangers are modeled.
Valeriy A Kuznetsov +3 more
doaj
On Darboux's Approach to R-Separability of Variables
Symmetry, Integrability and Geometry: Methods and Applications, 2011 We discuss the problem of R-separability (separability of variables with a factor R) in the stationary Schrödinger equation on n-dimensional Riemann space.
Adam Szereszewski, Antoni Sym
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Superintegrable Stäckel Systems on the Plane: Elliptic and Parabolic Coordinates
Symmetry, Integrability and Geometry: Methods and Applications, 2012 Recently we proposed a generic construction of the additional integrals of motion for the Stäckel systems applying addition theorems to the angle variables.
Andrey V. Tsiganov
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source