Results 71 to 80 of about 1,287,809 (281)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Symmetric separation of variables for trigonometric integrable models

open access: yesNuclear Physics B, 2020
We study a problem of variable separation for the classical integrable hamiltonian systems possessing Lax matrices satisfying linear r-matrix algebra with skew-symmetric sl(2)⊗sl(2)-valued trigonometric r-matrix.
T. Skrypnyk
doaj   +1 more source

On the bi-Hamiltonian structure of Bogoyavlensky system on $so(4)$

open access: yes, 2010
We discuss bi-Hamiltonian structure for the Bogoyavlensky system on $so(4)$ with an additional integral of fourth order in momenta. An explicit procedure to find the variables of separation and the separation relations is considered in ...
Vershilov, A. V.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Implementing parallel elliptic solver on a Beowulf cluster

open access: yesElectronic Journal of Differential Equations, 1999
In a recent paper cite{zara} a parallel direct solver for the linear systems arising from elliptic partial differential equations has been proposed. The aim of this note is to present the initial evaluation of the performance characteristics of this ...
Marcin Paprzycki   +2 more
doaj  

Separation of Variables and Contractions on Two-Dimensional Hyperboloid

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2012
In this paper analytic contractions have been established in the R→∞ contraction limit for exactly solvable basis functions of the Helmholtz equation on the two-dimensional two-sheeted hyperboloid. As a consequence we present some new asymptotic formulae.
Ernie Kalnins   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Some Counterexamples to Separation of Variables

open access: yesJournal of Differential Equations, 1995
An algebraic PDE system admits separation of variables if it has at least one differentially algebraic (DA) solution. Here a function is DA if there is a field of finite transcendence degree over \(\mathbb{C}\) that contains this function and all its partial derivatives.
Johnson, J., Reinhart, G.M., Rubel, L.A.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Complex variables for separation of Hamilton-Jacobi equation on real pseudo-Riemannian manifolds

open access: yes, 2006
In this paper the geometric theory of separation of variables for time-independent Hamilton-Jacobi equation is extended to include the case of complex eigenvalues of a Killing tensor on pseudo-Riemannian manifolds.
Degiovanni, Luca, Rastelli, Giovanni
core   +1 more source

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