Results 91 to 100 of about 105,930 (282)

Chemical Synthesis and Structural Determination of the Inositol Glycan Head of Plant Sphingolipid GIPC in Brassicaceae

open access: yesChemistry – A European Journal, Volume 31, Issue 55, October 1, 2025.
The first experimental identification of the IG head structure of naturally occurring plant GIPCs in Brassicaceae was achieved through the chemical synthesis of three hexose‐type IGs containing d‐glucose, d‐galactose, or d‐mannose as the second monosaccharide linked to d‐glucuronic acid‐α(1→2)‐myo‐inositol.
Yuta Umemura   +11 more
wiley   +1 more source

Akkermansia muciniphila‐derived hypoacylated rough‐type lipopolysaccharides alleviate diet‐induced obesity via activation of TLR4−IL‐23−IL‐22 immune axis

open access: yesiMeta, Volume 4, Issue 5, October 2025.
This study demonstrates that hypoacylated, rough‐type lipopolysaccharides (LPS) derived from Akkermansia muciniphila strain HW07 (ALPS) alleviates diet‐induced obesity. ALPS acts as a weak TLR4 agonist and significantly reduces weight gain, improves metabolic parameters, and restores gut barrier integrity in obese mice.
Li Sun   +14 more
wiley   +1 more source

Chemical Coupling of Amino Acids, Peptides, and Proteins to Sephadex. [PDF]

open access: bronze, 1964
Rolf Axén   +3 more
openalex   +1 more source

Synergistic inhibition of α‐glucosidase and α‐amylase by phenolic compounds isolated from olive oil by‐products

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 13, Page 7591-7597, October 2025.
Abstract BACKGROUND The inhibition of carbohydrate‐digesting enzymes, α‐glucosidase and α‐amylase, is a key strategy in managing postprandial hyperglycemia in type 2 diabetes. Natural phenolic compounds isolated from olive mill by‐product (alperujo), such as hydroxytyrosol (HT) and trans‐p‐coumaroyl secologanoside (comselogoside, COM), have shown ...
Fátima Rubio‐Senent   +4 more
wiley   +1 more source

Chromatography of Conjugated Steroids on Lipophilic Sephadex. [PDF]

open access: bronze, 1966
Jan Sjövall   +7 more
openalex   +1 more source

Amphiphilic Poly(γ‐glutamic acid) Derivatives for Delivering Doxorubicin in Cancer Cells

open access: yesMacromolecular Bioscience, Volume 25, Issue 10, October 2025.
In this study, poly(γ‐glutamic acid) was modified via esterification with 4‐phenyl‐butyl bromide to enhance its amphiphilic properties, enabling self‐assembly into nanoparticles (NPs). Further functionalization with hydrophilic groups (MethoxyPEG) and targeting ligands (Folic acid‐PEG) (FA‐PEG) provided NPs that were loaded with DOX and delivered in U ...
Porochista Dorost   +5 more
wiley   +1 more source

Proteolytic stabilization of a spider venom peptide results in an orally active bioinsecticide

open access: yesPest Management Science, Volume 81, Issue 10, Page 6404-6415, October 2025.
Selective editing out of an insect gut protease cleavage site renders a spider‐derived insecticidal peptide active by ingestion by insect pests. Abstract BACKGROUND The toxin peptide U1‐AGTX‐Ta1b from the Hobo spider, Eratigena agrestis (Walckenaer, 1802), was studied to determine its potential to serve as a bioinsecticide.
Breck R. Davis   +12 more
wiley   +1 more source

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