Results 51 to 60 of about 163,198 (278)

Olive‐derived bioactive combinations: synergistic angiotensin‐I‐converting enzyme (ACE) inhibition and distinct mechanisms of triterpenic acids and phenolics

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Cardiovascular diseases, largely driven by hypertension, remain the leading cause of mortality worldwide. Angiotensin‐I‐converting enzyme (ACE) inhibition is a well‐established therapeutic approach; however, synthetic inhibitors are frequently associated with adverse effects.
Fátima Rubio‐Senent   +5 more
wiley   +1 more source

Impact of antibacterial drugs on human serum paraoxonase-1 (hPON1) activity: an in vitro study

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2014
Objective: To investigate the in vitro effects of the antibacterial drugs, meropenem trihydrate, piperacillin sodium, and cefoperazone sodium, on the activity of human serum paraoxonase (hPON1).
Hakan Söyüt   +2 more
doaj   +1 more source

Poly(2‐Oxazoline)‐Based Polyphotoacids: Synthesis, Solution Behavior, and Cellular Uptake of Multi‐Responsive Intracellular Transporters

open access: yesMacromolecular Rapid Communications, EarlyView.
The ability of photoacids to increase their acidity in response to light irradiation (excited state proton transfer, ESPT) makes them attractive building blocks for the design of stimuli‐responsive copolymers. In this contribution, we present highly biocompatible polyphotoacids based on poly(2‐oxazoline)s bearing 1‐hydroxypyrene units. Low cytotoxicity,
Leonid I. Kaberov   +7 more
wiley   +1 more source

A proanthocyanidin from cinnamomum zeylanicum stimulates phosphorylation of insulin receptor in 3t3-l1 adipocytes [PDF]

open access: yes, 2006
Non-insulin-dependent diabetes mellitus is due to in large part to insulin resistance, a state where the target cells are no longer responding to ordinary levels of circulating insulin.
Abdul Majid, Fadzilah Adibah   +2 more
core   +1 more source

Trypsin inhibitor from starchy endosperm of rye seeds

open access: yesActa Societatis Botanicorum Poloniae, 2015
A method for the preparation of a trypsin inhibitor from starchy endosperm of rye seeds is described. Isolation and purification comprised the following steps: salting out of the water-soluble proteins at pH 4.5 with ammonium sulphate (0.4 saturation ...
A. Pawłowski
doaj   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

The development of a purification procedure for Peptide:n-Glycosidase A from Prunus amygdalus : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

open access: yes, 1997
Peptide-N4-acetyl-β-glucosaminyl) asparagine amidases cleave the amide bond between N-linked glycans at N-acetylglucosamine and asparagine, liberating intact oligosaccharide chains from glycoproteins. Although PNGase A is commonly used by glycobiologists
Diepen, Angela Corinne van
core  

Biogenesis of Glyoxysomes [PDF]

open access: yes, 1980
Biosynthesis of isocitrate lyase, a tetrameric enzyme of the glyoxysomal matrix, was studied in Neurospora crassa, in which the formation of glyoxysomes was induced by a substitution of sucrose medium by acetate medium. * 1.
Neupert, Walter, Zimmermann, Richard
core   +1 more source

Purification of some active ingredients of alcoholic extract of anise seed (Pimpinella anisum) and assessment their estrogenic effect on some physiological traits of immature female mice

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2009
This experiment was conducted in order to purify some active ingredients of 70% alcoholic extract of aniseed by adsorption chromatography on silica gel and gel filtration on sepharose CL-6B column, using phosphate buffer (0.1M, pH 7.0) as eluent, as ...
Anwar I. obead   +2 more
doaj   +1 more source

Structural Modeling and Dynamics of the Full‐Length Homer1 Multimer

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Homer proteins are modular scaffold molecules that constitute an integral part of the protein network within the postsynaptic density. Full‐length Homer1 forms a large homotetramer via a long coiled coil region, and can interact with proline‐rich target sequences with its globular EVH1 domain.
Zsófia E. Kálmán   +9 more
wiley   +1 more source

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