Results 71 to 80 of about 160,374 (321)

Synergistic inhibition of α‐glucosidase and α‐amylase by phenolic compounds isolated from olive oil by‐products

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The inhibition of carbohydrate‐digesting enzymes, α‐glucosidase and α‐amylase, is a key strategy in managing postprandial hyperglycemia in type 2 diabetes. Natural phenolic compounds isolated from olive mill by‐product (alperujo), such as hydroxytyrosol (HT) and trans‐p‐coumaroyl secologanoside (comselogoside, COM), have shown ...
Fátima Rubio‐Senent, Alejandra Bermúdez‐Oria, Antonio Lama‐Muñoz, Guillermo Rodríguez‐Gutiérrez, Juan Fernández‐Bolaños   +4 more
wiley   +1 more source

Amphiphilic Poly(γ‐glutamic acid) Derivatives for Delivering Doxorubicin in Cancer Cells

Macromolecular Bioscience, EarlyView.
In this study, poly(γ‐glutamic acid) was modified via esterification with 4‐phenyl‐butyl bromide to enhance its amphiphilic properties, enabling self‐assembly into nanoparticles (NPs). Further functionalization with hydrophilic groups (MethoxyPEG) and targeting ligands (Folic acid‐PEG) (FA‐PEG) provided NPs that were loaded with DOX and delivered in U ...
Porochista Dorost, Miguel R. G. Morais, Sofia Cunha Guimarães, Ana Paula Pêgo, Montserrat García‐Alvarez, Antxon Martínez de Ilarduya   +5 more
wiley   +1 more source

A neutrophil-dependent pathway for the generation of a neutral peptide mediator: partial characterization of components and control by alpha-1-antitrypsin. [PDF]

, 1974
A biologically active neutral peptide mediator is cleaved from a plasma protein substrate by an alpha-1-antitrypsin-inhibitable serine protease apparently residing on the membrane of the human neutrophil. The peptide mediator has an approximate mol wt of
Austen, KF, Goetzl, EJ, Wintroub, BU
core  

Transport of Proteins into Mitochondria [PDF]

, 1980
The mitochondrial ADP/ATP carrier is an integral transmembrane protein of the inner membrane. It is synthesized on cytoplasmic ribosomes. Kinetic data suggested that this protein is transferred into mitochondria in a posttranslational manner.
Allen E. H., Brdiezka D., Chang C. N., Chang C. N., Conboy J. G., Cote C., Date T., Dobberstein B., Flavell R. B., Habermann E., Hackenberg H., Hallermayer G., Harmey M. A., Highfield P. E., Ito K., Klingenberg M., Knoppel E., Korb H., Kreil G., Laemmli U. K., Maccechini M. L., Maccechini M.-L., Mandel G., Marra E., Michel R., Milstein C., Mori M., Nelson N., Pelham H. R. B., Poyton R. O., Poyton R. O., Raymond Y., Schatz G., Sessa G., Shore G. S., Strauss A. W., Vignais P. V., Wickner W., Wickner W., Williams J. C., Zimmermann R., Zimmermann R.   +41 more
core   +1 more source

Antifungal Activity of an Abundant Thaumatin-Like Protein from Banana against Penicillium expansum, and Its Possible Mechanisms of Action

Molecules, 2018
Thaumatin-like protein from banana (designated BanTLP) has been purified by employing a simple protocol consisting of diethylaminoethyl Sephadex (DEAE–Sephadex) chromatography, gel filtration on Sephadex G50, and reversed-phase chromatography.
Wenxiao Jiao, Xiangxin Li, Handong Zhao, Jiankang Cao, Weibo Jiang   +4 more
doaj   +1 more source

Liposomes Containing Tetraether Lipids and Cell‐Penetrating Peptides as Platform Technology for Oral Delivery of Peptides: A Comparative Study on GLP‐1 Analogs

Nano Select, EarlyView.
Liposomes functionalized with tetraether lipids and cell‐penetrating peptides are explored as a platform technology for oral peptide delivery. Therefore, peptide drugs (GLP‐1 analogs) with different sizes and physicochemical properties are used as model drugs.
Lorenz Herbster, Giulia Pander, Manuel Ben Böhmann, Tom Eisenzapf, Sabrina Wohlfart, Eric Mühlberg, Walter Mier, Gert Fricker, Philipp Uhl   +8 more
wiley   +1 more source

The development of a purification procedure for Peptide:n-Glycosidase A from Prunus amygdalus : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1997
Peptide-N4-acetyl-β-glucosaminyl) asparagine amidases cleave the amide bond between N-linked glycans at N-acetylglucosamine and asparagine, liberating intact oligosaccharide chains from glycoproteins. Although PNGase A is commonly used by glycobiologists
Diepen, Angela Corinne van
core  

The effect of N‐oxide phenazine producer Lysobacter antibioticus on bacterial leaf streak in rice and the rhizosphere microbial community

New Plant Protection, EarlyView.
Lysobacter antibioticus OH13 and its antibiotic myxin effectively control rice bacterial leaf streak (BLS) under greenhouse conditions and in field trials. OH13 alters the rhizosphere microbiome, enriching beneficial bacteria. Myxin production was boosted 3.19‐fold via mutagenesis and optimization, highlighting the potential of OH13 as a sustainable ...
Junjing Chen, Xinyi Cheng, Gaoge Xu, Yancun Zhao, Fengquan Liu, Yangyang Zhao   +5 more
wiley   +1 more source

Studies of the binding of different iron donors to human serum transferrin and isolation of iron-binding fragments from the N- and C-Terminal regions of the protein [PDF]

, 1978
1. Trypsin digestion of human serum transferrin partially saturated with iron(III)- nitrilotriacetate at pH5.5 or pH 8.5 produces a carbohydrate-containing iron-binding fragment of mol.wt. 43000. 2. When iron(III) citrate, FeCI3, iron(II) ascorbate and
Evans, RW, Williams, J
core   +2 more sources

Anti‐Inflammatory Saponins From an Edible Aquatic Plant Nymphoides hydrophylla

Phytochemical Analysis, EarlyView.
ABSTRACT Introduction The present investigation of Nymphoides hydrophylla is a Taiwan indigenous edible aquatic plant, belongs to the Menyanthaceae family, and has been used as a traditional food with potential medicinal values against fever, insect bites, ulcer, and skin diseases.
Ching‐Yeu Chen, Tzu‐Peng Cheng, Tsong‐Long Hwang, Yong‐Siang Hou, Limbadri Salendra, Tzi‐Yi Ke, Yuan‐Bin Cheng   +6 more
wiley   +1 more source