Results 11 to 20 of about 1,918 (162)

The Structure of Hemicalide from the Marine Sponge Hemimycale sp

open access: yesEuropean Journal of Organic Chemistry, Volume 2022, Issue 25, July 7, 2022., 2022
Hemicalide, isolated from the marine sponge Hemimycale sp., is a very potent cytotoxic compound from a marine sponge with an original mode of action. Its planar structure has been established by NMR and a proposal for 17 of its 21 stereogenic centers is made on the basis of syntheses of analogues.
Laurence Marcourt, Georges Massiot
wiley   +1 more source

GNPS‐Guided Discovery of Madurastatin Siderophores from the Termite‐Associated Actinomadura sp. RB99**

open access: yesChemistry – A European Journal, Volume 28, Issue 36, June 27, 2022., 2022
Metabolomic analysis of cocultures of Actinomadura sp. RB99 with fungal symbionts of termites allowed for the MS‐guided isolation of four unreported madurastatin derivatives, including a siderophore‐metal complex thereof. Abstract In this study, we analyzed if Actinomadura sp.
Seoung Rak Lee   +9 more
wiley   +1 more source

Characterization of the diastaphenazine/izumiphenazine C biosynthetic gene cluster from plant endophyte Streptomyces diastaticus W2

open access: yesMicrobial Biotechnology, Volume 15, Issue 4, Page 1168-1177, April 2022., 2022
In this study, we identified the diastaphenazine/izumiphenazine C biosynthetic gene cluster through heterologous expression and gene inactivation. The putative biosynthetic pathway of these two compounds was proposed by further functional analysis. Significantly, the polyketide cyclase Dap5 has been proven to be responsible for the dimerization of two ...
Junli Dong   +7 more
wiley   +1 more source

Insecticidal characteristics and structural identification of the potential active compounds from Streptomyces sp. KR0006: Strain improvement through mutagenesis

open access: yesPLoS ONE, 2022
Pest control by biological means is an effective, eco-friendly, and promising method that typically involves compounds naturally derived from actinomycetes. Thus, the present study aimed to screen, characterize, and identify the structure of insecticidal
Young Sook Kim   +4 more
doaj   +2 more sources

Chemical Constituents of the Bark of Zanthoxylum gilletii (Rutaceae) and Their In Vitro Antiplasmodial and Molecular Docking Studies

open access: yesJournal of Chemistry, Volume 2022, Issue 1, 2022., 2022
The phytochemical investigations of the methanol extract of Zanthoxylum gilletii bark led to the isolation of thirteen compounds identified as two alkaloids including one acridone 5‐hydroxynoracronycine (1) and one benzo [c] phenanthridine decarine (2), three lignans trans‐ and cis‐fagaramide (3 and 4) and sesamin (5), two coumarins scoparone (6) and ...
Liliane Clotilde Dzouemo   +8 more
wiley   +1 more source

Bioactive components of endophytic fungi from two Hainan mangrove plants

open access: yesShenzhen Daxue xuebao. Ligong ban, 2022
Mangrove endophytic fungi are one of the important sources for discovering natural drug leads. In order to obtain natural compounds with novel structures, the metabolites of two mangrove endophytic fungi Phomopsis sp.
CHEN Biting   +7 more
doaj   +1 more source

Biological Properties of Aloysia gratissima (Gillies & Hook.) Tronc. (Verbenaceae)

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Aloysia gratissima is a plant native to America, with applications in folk medicine for a wide range of diseases, such as bronchial infections, lung disorders, nervous system disorders (depression, anxiety), and inflammatory processes, among others. However, investigations about this species and its biological actions are still scarce.
Maryelen Alijar Souza   +5 more
wiley   +1 more source

Antioxidant and Anti‐Inflammatory Activities of Phytochemicals from Ruellia tuberosa

open access: yesJournal of Chemistry, Volume 2022, Issue 1, 2022., 2022
In Vietnam, the aerial parts of Ruellia tuberosa L. are used to treat stress oxidation and inflammatory symptoms in diabetes mellitus. The present study was designed to determine the antioxidant and inflammatory inhibition activities of Ruellia tuberosa L. extract (RTE) and those of the isolated compounds by column chromatography.
Trinh Nhat Thi Pham   +7 more
wiley   +1 more source

Isolation and Characterization of Antibacterial Compounds from Aspergillus fumigatus: An Endophytic Fungus from a Mangrove Plant of the Sundarbans

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
The Sundarbans, a UNESCO world heritage site, is one of the largest mangrove forests in one stretch. Mangrove plants from this forest are little studied for their endophytic fungi. In this study, we isolated fourteen endophytic fungi from the plants Ceriops decandra and Avicennia officinalis collected from the Sundarbans.
S. M. Neamul Kabir Zihad   +9 more
wiley   +1 more source

Membrane composition is a functional determinant of NIR‐activable liposomes in orthotopic head and neck cancer

open access: yesNanophotonics, Volume 10, Issue 12, Page 3169-3185, September 2021., 2021
Abstract Near‐infrared (NIR)‐activable liposomes containing photosensitizer (PS)‐lipid conjugates are emerging as tunable, high‐payload, and tumor‐selective platforms for photodynamic therapy (PDT)‐based theranostics. To date, the impact that the membrane composition of a NIR‐activable liposome (the chemical nature and subsequent conformation of PS ...
Mina Guirguis   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy