Results 181 to 190 of about 169,356 (299)

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Severe obesity in human HFpEF alters contractile protein function and organization. [PDF]

Science
Jani VP, Rhodehamel M, Fenwick AJ, Ma W, Fisher E, Giannakopoulos MT, Moon S, Castillo RL, Kennedy LM, Irving TC, Tardiff JC, Murphy E, Chaerkady R, Wang Q, Barry ME, Hahn VS, Sharma K, Margulies KB, Bedi KC, Cammarato A, Kass DA.   +20 more
europepmc   +1 more source

Identification of a novel high‐prevalence red blood cell antigen on junctional adhesion molecule‐A defines a new blood group system

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Availability of new technologies has accelerated the pace of blood group discovery, with nine of 48 known systems being discovered in the past 5 years alone, and yet uncharacterized antigens remain. This study involved investigations of samples from a female patient presenting with a moderate strength pan‐reactive ...
Tosti J. Mankelow, Louise A. Tilley, Vanja Karamatic Crew, Benjamin Jones, Marina Izak, Liora Muncher, Vered Yahalom, Nicole M. Thornton   +7 more
wiley   +1 more source

Extraction and Isolation of Extracellular Vesicles From <i>Piper betle</i> Leaves Using the Apoplastic Fluid Washing and Size Exclusion Chromatography Method. [PDF]

Bio Protoc
Sanddy I, Adawiyah WR, Ooi J, Ekanayake G, Fazeli A, Rahman NIA, Khan NLA.   +6 more
europepmc   +1 more source

METTL18 is Required for Developmental, Metabolic, and Endocrine Regulation of Mammalian Growth

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
METTL18 is essential for histidine Nτ‐methylation of proteins, normal embryonic development, iron and lipid metabolism, and hormone signaling pathways that support postnatal growth in mice. The main points of this study are as follows: First, mouse METTL18 catalyzes histidine Nτ‐methylation. Next, Mettl18 KO embryos are significantly smaller than their
Fumiya Kasai, Jun‐Dal Kim, Koichiro Kako, Naoto Muromachi, Takeru Saito, Yao Yuan, Hayase Mizukami, Nana Kishikawa, Kanako Nakamura, Kaori Motomura, Hiroaki Daitoku, Yuuki Imai, Sho Sekiguchi, Kazuhiko Horiguchi, Satoshi Narumi, Masanobu Yamada, Akiyoshi Fukamizu   +16 more
wiley   +1 more source

Efficient refolding, purification, and characterization of barley oxalate oxidase in Escherichia coli. [PDF]

Microb Cell Fact
Donelan W, Li S, Dominguez-Gutierrez PR, Tang D, Yang LJ, Canales BK.   +5 more
europepmc   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

The host DHX29 RNA helicase regulates HCMV immediate-early protein synthesis. [PDF]

mBio
Lenarcic EM, Moorman NJ.
europepmc   +1 more source

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, Volume 13, Issue 50, 7 September 2026.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

A Rapid Genomic DNA Extraction Method for Direct Quantitative Polymerase Chain Reaction-Based On-Site Detection of Soil-Borne Fungal Disease. [PDF]

Plant Pathol J
Kwon G, Hong D, Lian S, Yu J, Kim KH.
europepmc   +1 more source