Results 11 to 20 of about 326,876 (283)

Effect of interferon-alpha on experimental septal fibrosis of the liver - study with a new model [PDF]

Memorias do Instituto Oswaldo Cruz, 2001
Interferon-alpha is used in antiviral therapy in humans, mainly for viral hepatitis B and C. An anti-fibrotic effect of interferon has been postulated even in the absence of anti-viral response, which suggests that interferon directly inhibits ...
Marcia Maria de Souza, Raymundo Paraná, Christian Trepo, Aryon A Barbosa Jr, Irismar Oliveira, Zilton A Andrade   +5 more
doaj   +4 more sources

Nonischemic Septal Fibrosis in Functional Tricuspid Regurgitation Provides Incremental Stratification of Adverse Remodeling and Prognosis [PDF]

JACC: Cardiovascular Imaging
Functional tricuspid regurgitation (TR) arises from impaired valve integrity resulting from contractile dysfunction, chamber dilation, or myocardial tissue alterations. Whereas right ventricular (RV) dysfunction is a recognized driver of adverse outcomes in TR, the impact of myocardial tissue injury, particularly nonischemic septal fibrosis (NIsF ...
Pablo Villar-Calle, Varun Pai, Robert S. Zhang, Mahniz Reza, Lily Jin, Rachel Axman, Zachary Falk, Giorgia Falco, Arindam RoyChoudhury, Shmuel Chen, Bobak Mosadegh, Susheel K. Kodali, Omar K. Khalique, Evelyn M. Horn, Jonathan W. Weinsaft, Jiwon Kim   +15 more
openaire   +3 more sources

Microstructural disease and hypoperfusion in dilated cardiomyopathy underpin midwall septal fibrosis [PDF]

Journal of Cardiovascular Magnetic Resonance
Fiona TS Chan, Sam Coveney, Sean L. Zheng, Matthew Webber, George Joy, Hunain Shiwani, Constantin-Cristian Topriceanu, Debbie Falconer, Emma Martin, Matthew Stanley, Iain Pierce, Irvin Teh, Jurgen Schneider, Christopher Nguyen, Alun D. Hughes, James C. Moon, Pier D. Lambiase, Peter Kellman, Erica Dall’Armellina, Gabriella Captur   +19 more
openaire   +2 more sources

Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain [PDF]

, 2013
Brain damage caused by an acute injury depends on the initial severity of the injury and the time elapsed after the injury. To determine whether these two variables activate common mechanisms, we compared the response of the rat medial septum to insult ...
Andrés, N., Prats Galino, Alberto, Pugliese, Marco, Rodríguez Allué, Manuel José, Mahy Gehenne, Josette Nicole, Malpesa, Y., Batlle, Montserrat   +6 more
core   +7 more sources

Targeted exhaled breath analysis for detection of Pseudomonas aeruginosa in cystic fibrosis patients [PDF]

, 2021
Background Pseudomonas aeruginosa (PA) is an important respiratory pathogen for cystic fibrosis (CF) patients. Routine microbiology surveillance is time-consuming, and is best performed on expectorated sputum. As alternative, volatile organic compounds (
Davies, Jane, Gerritsen, Marije, Lammers, Ariana, Kraneveld, Aletta, Neerincx, Anne, Janssens, Hettie, Haarman, Eric, on behalf of the Amsterdam Mucociliary Clearance Disease (AMCD) Research Group and the Amsterdam UMC Breath Research Group, Weersink, Els, Maitland-van der Zee, Anke, Majoor, Christof, Sterk, Peter, Kos, Renate, Brinkman, Paul, Paff, Tamara, Bos, Lieuwe, Heijerman, Harry   +16 more
core   +1 more source

Association Between Left Ventricular Mechanical Deformation and Myocardial Fibrosis in Nonischemic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background In patients with nonischemic cardiomyopathy, nonischemic fibrosis detected by late gadolinium enhancement (LGE) cardiovascular magnetic resonance is related to adverse cardiovascular outcomes.
Ibolya Csecs, Farhad Pashakhanloo, Amanda Paskavitz, Jihye Jang, Talal Al‐Otaibi, Ulf Neisius, Warren J. Manning, Reza Nezafat   +7 more
doaj   +1 more source

Progressive Right Ventricular Obstruction Caused by a Double-Chambered Right Ventricle Resulting in Shunt-Reversal via a Concomitant Congenital Ventricular Septal Defect and Subsequent Erythrocytosis in a Dog

Veterinary Sciences, 2023
A 3-year-old Chihuahua was presented because of exercise intolerance, respiratory distress, and syncopal episodes. At the age of 10 weeks, the dog was diagnosed with a congenital small left-to-right shunting ventricular septal defect and a mild right ...
Viktor Szatmári, Mark Dirven, Heike Aupperle-Lellbach   +2 more
doaj   +1 more source

Comparison of typical and atypical computed tomography patterns regarding reversibility and fibrosis in pulmonary sarcoidosis

Annals of Thoracic Medicine, 2021
PURPOSE: This study aims to investigate whether there is a significant difference between typical and atypical parenchymal patterns in the development of fibrosis, which is the most crucial factor affecting morbidity in pulmonary sarcoidosis. METHODS: In
Seher Susam, Fatma Demirci Ucsular, Enver Yalniz, Akin Cinkooglu, Gulru Polat, Berna Eren Komurcuoglu, Ceyda Anar, Gulistan Karadeniz, Ali Kadri Cirak, Emel Tellioglu, Filiz Guldaval, Mine Gayaf, Nimet Aksel, Ozgur Batum, Dursun Alizoroglu, Semra Bilaceroglu   +15 more
doaj   +1 more source

Creation of ventricular septal defects on the beating heart in a new pig model [PDF]

, 2008
Background/ Aims: So far, surgical and interventional therapies for muscular ventricular septal defects ( mVSDs) beyond the moderator band have had their limitations. Thus, alternative therapeutic strategies should be developed.
Hinterseer, M., Rassoulian, D., Sodian, R., Lang, N., Aumann, R., Netz, H., Kozlik-Feldmann, R., Schmitz, C.   +7 more
core   +1 more source

Pathogenesis of hepatic septal fibrosis associated with Capillaria hepatica infection of rats Patogenia da fibrose septal hepática associada com a infecção por Capillaria hepatica em ratos

Revista da Sociedade Brasileira de Medicina Tropical, 2001
Septal fibrosis is a common form of hepatic fibrosis, but its etiology and pathogenesis are poorly understood. Rats infected with the helminth Capillaria hepatica constitute a good experimental model of such fibrosis.
Antônio Benigno dos Santos, Miguel Tolentino Junior, Zilton A. Andrade   +2 more
doaj   +1 more source