Capillaria hepatica-induced septal fibrosis in rats: a contribution to the study of liver fibrogenesis Contribuição para o estudo da fibrogenesis hepática em ratos infectados com Capillaria hepatica [PDF]
INTRODUCTION: Septal fibrosis of the liver regularly develops in rats infected with the nematode Capillaria hepatica. Curative treatment of the infection prevents the development of septal fibrosis when intervention occurs up to postinfection day (PID ...
Valter Lucas Chaves Barbosa +1 more
doaj +5 more sources
Effect of interferon-alpha on experimental septal fibrosis of the liver - study with a new model [PDF]
Interferon-alpha is used in antiviral therapy in humans, mainly for viral hepatitis B and C. An anti-fibrotic effect of interferon has been postulated even in the absence of anti-viral response, which suggests that interferon directly inhibits ...
Marcia Maria de Souza +5 more
doaj +4 more sources
Production of septal fibrosis of the liver by means of foreign protein injections into rats [PDF]
Similarities and differences in antigenic humoral responses and electrophoretic patterns between Capillaria hepatica and pig-serum were investigated as a contribution to the understanding of hepatic fibrosis induced by the parenteral administration of ...
Bruna Magalhães Gotardo +3 more
doaj +5 more sources
Immunological basis of septal fibrosis of the liver in Capillaria hepatica-infected rats [PDF]
Rats infected with the helminth Capillaria hepatica regularly develop septal fibrosis of the liver similar to that induced by repeated ip injections of pig serum.
Lemos Q.T. +2 more
doaj +5 more sources
Microstructural disease and hypoperfusion in dilated cardiomyopathy underpin midwall septal fibrosis. [PDF]
The presence of midwall septal fibrosis (MSF) in dilated cardiomyopathy (DCM) has been shown to be associated with adverse clinical outcomes, but the underlying pathophysiological mechanisms are incompletely understood. We investigated whether MSF associates with a distinct pattern of myocardial microstructural and microvascular abnormalities using ...
Chan FT +19 more
europepmc +3 more sources
Influence of the route of administration of pig-serum in the induction of hepatic septal fibrosis in rats [PDF]
Zilton A Andrade, Adriana Godoy
doaj +3 more sources
Nonischemic Septal Fibrosis in Functional Tricuspid Regurgitation Provides Incremental Stratification of Adverse Remodeling and Prognosis. [PDF]
Functional tricuspid regurgitation (TR) arises from impaired valve integrity resulting from contractile dysfunction, chamber dilation, or myocardial tissue alterations. Whereas right ventricular (RV) dysfunction is a recognized driver of adverse outcomes in TR, the impact of myocardial tissue injury, particularly nonischemic septal fibrosis (NIsF ...
Villar-Calle P +15 more
europepmc +3 more sources
PURPOSE: This study aims to investigate whether there is a significant difference between typical and atypical parenchymal patterns in the development of fibrosis, which is the most crucial factor affecting morbidity in pulmonary sarcoidosis. METHODS: In
Seher Susam +15 more
doaj +1 more source
Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver disease. [PDF]
Galectin-3 protein is critical to the development of liver fibrosis because galectin-3 null mice have attenuated fibrosis after liver injury. Therefore, we examined the ability of novel complex carbohydrate galectin inhibitors to treat toxin-induced ...
Peter G Traber +6 more
doaj +1 more source
Systhematized septal fibrosis of the liver can be induced in rats either by repeated intraperitoneal injections of pig-serum or by Capillaria hepatica infection.
Rodrigo Guimarães Andrade +4 more
doaj +1 more source

