Results 21 to 30 of about 34,118 (151)

Experimental Right Ventricular Hypertension Induces Regional β1‐Integrin–Mediated Transduction of Hypertrophic and Profibrotic Right and Left Ventricular Signaling

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundDevelopment of right ventricular (RV) hypertension eventually contributes to RV and left ventricular (LV) myocardial fibrosis and dysfunction. The molecular mechanisms are not fully elucidated.
Mei Sun, Ryo Ishii, Kenichi Okumura, Adrienn Krauszman, Siegfried Breitling, Olga Gomez, Aleksander Hinek, Stellar Boo, Boris Hinz, Kim A. Connelly, Wolfgang M. Kuebler, Mark K. Friedberg   +11 more
doaj   +1 more source

Presence of contractile impairment appears crucial for structural remodeling in idiopathic left bundle-branch block

Journal of Cardiovascular Magnetic Resonance, 2021
Background To differentiate effects of ventricular asynchrony from an underlying hypocontractile cardiomyopathy this study aimed to enhance the understanding of functional impairment and structural remodeling in idiopathic left bundle-branch block (LBBB).
Janek Salatzki, Theresa Fischer, Johannes Riffel, Florian André, Kristóf Hirschberg, Andreas Ochs, Hauke Hund, Matthias Müller-Hennessen, Evangelos Giannitsis, Matthias G. Friedrich, Eberhard Scholz, Norbert Frey, Hugo A. Katus, Marco Ochs   +13 more
doaj   +1 more source

Hepatic capillariasis in rats: a new model for testing antifibrotic drugs

Brazilian Journal of Medical and Biological Research, 2000
Rats infected with the helminth Capillaria hepatica regularly develop septal hepatic fibrosis that may progress to cirrhosis in a relatively short time.
M.M. de Souza, L.M. Silva, A.A. Barbosa Jr., I.R. de Oliveira, R. Paraná, Z.A. Andrade   +5 more
doaj   +1 more source

Comparison of echocardiography with tissue Doppler imaging and magnetic resonance imaging with delayed enhancement in the assessment of children with hypertrophic cardiomyopathy

Archives of Medical Science, 2016
Introduction : In children with hypertrophic cardiomyopathy (HCM) there often occurs a non-ischemic pattern of myocardial fibrosis, which could be the cause of impaired left ventricular (LV) diastolic function assessed by tissue Doppler imaging (TDI ...
Lidia Ziółkowska, Joanna Petryka, Agnieszka Boruc, Wanda Kawalec   +3 more
doaj   +1 more source

Second-Harmonic Generated Quantifiable Fibrosis Parameters Provide Signatures for Disease Progression and Regression in Nonalcoholic Fatty Liver Disease

Clinical Pathology, 2023
Introduction: The current ordinal fibrosis staging system for nonalcoholic steatohepatitis (NASH) has a limited dynamic range. The goal of this study was to determine if second-harmonic generated (SHG) quantifiable collagen fibrillar properties (qFP) and
Nicole Ng, Dean Tai, Yayun Ren, Elaine Chng, Mulugeta Seneshaw, Faridoddin Mirshahi, Michael Idowu, Amon Asgharpour, Arun J Sanyal   +8 more
doaj   +1 more source

Immunological tolerance to pig-serum partially inhibits the formation of septal fibrosis of the liver in Capillaria hepatica-infected rats

Memorias do Instituto Oswaldo Cruz, 2004
Systhematized septal fibrosis of the liver can be induced in rats either by repeated intraperitoneal injections of pig-serum or by Capillaria hepatica infection.
Rodrigo Guimarães Andrade, Bruna Magalhães Gotardo, Bárbara Cristina A Assis, José Mengel, Zilton A Andrade   +4 more
doaj   +1 more source

[RETRACTED ARTICLE] Characteristics of liver fibrosis with different etiologies using a fully quantitative fibrosis assessment tool

Brazilian Journal of Medical and Biological Research
This study aimed to test the diagnostic performance of a fully quantitative fibrosis assessment tool for liver fibrosis in patients with chronic hepatitis B (CHB), primary biliary cirrhosis (PBC) and non-alcoholic steatohepatitis (NASH).
Q. Wu, X. Zhao, H. You
doaj   +1 more source

Morphogenesis of pericellular liver fibrosis in patients with chronic viral hepatitis C associated with hepatic steatosis

Patologìâ, 2012
The research of pathomorphological features of liver fibrosis in patients with chronic viral hepatitis C associated with hepatic steatosis has shown that as opposed to cases of perisinusoidal-central-lobular and portal-septal fibrosis, typical for ...
V. A. Tumanskiy, Yu. A. Shebeko, E. A. Gromenko, S. V. Fen’   +3 more
doaj   +1 more source

Hybrid CMR- and FDG-PET-Imaging Gives New Insights Into the Relationship of Myocardial Metabolic Activity and Fibrosis in Patients With Becker Muscular Dystrophy

Frontiers in Cardiovascular Medicine, 2022
BackgroundCardiac involvement in patients with Becker muscular dystrophy (BMD) is an important predictor of mortality. The cardiac phenotype of BMD patients is characterized by slowly progressive myocardial fibrosis that starts in the left ventricular ...
Volker Vehof, Volker Vehof, Florian Büther, Anca Florian, Stefanos Drakos, Bishwas Chamling, Peter Kies, Lars Stegger, Ali Yilmaz   +8 more
doaj   +1 more source

The characteristics and evolution of pulmonary fibrosis in COVID-19 patients as assessed by AI-assisted chest HRCT.

PLoS ONE, 2021
The characteristics and evolution of pulmonary fibrosis in patients with coronavirus disease 2019 (COVID-19) have not been adequately studied. AI-assisted chest high-resolution computed tomography (HRCT) was used to investigate the proportion of COVID-19
Jia-Ni Zou, Liu Sun, Bin-Ru Wang, You Zou, Shan Xu, Yong-Jun Ding, Li-Jun Shen, Wen-Cai Huang, Xiao-Jing Jiang, Shi-Ming Chen   +9 more
doaj   +1 more source