Results 91 to 100 of about 1,083,142 (408)

The Systemic Alterations of Lipids, Alanine-Glucose Cycle and Inter-Organ Amino Acid Metabolism in Swine Model Confirms the Role of Liver in Early Phase of Septic Shock

open access: yesFrontiers in Physiology, 2019
Septic shock is a medical emergency and is one of the main causes of mortality in critically ill patients. Given the pathophysiological complexity of sepsis spectrum and progression in clinical settings, animal models become essential tools to improve ...
Manuela Ferrario   +5 more
doaj   +1 more source

The Concentration of Large Extracellular Vesicles Differentiates Early Septic Shock From Infection

open access: yesFrontiers in Medicine, 2021
Septic shock represents a subset of sepsis with severe physiological aberrations and a higher mortality rate than sepsis alone. Currently, the laboratory tools which can be used to identify the state of septic shock are limited.
Latthawan Monnamorn   +6 more
doaj   +1 more source

Machine Learning Algorithms for Classification of Microcirculation Images from Septic and Non-Septic Patients [PDF]

open access: yes, 2018
Sepsis is a life-threatening disease and one of the major causes of death in hospitals. Imaging of microcirculatory dysfunction is a promising approach for automated diagnosis of sepsis. We report a machine learning classifier capable of distinguishing non-septic and septic images from dark field microcirculation videos of patients.
arxiv   +1 more source

Offline reinforcement learning with uncertainty for treatment strategies in sepsis [PDF]

open access: yesarXiv, 2021
Guideline-based treatment for sepsis and septic shock is difficult because sepsis is a disparate range of life-threatening organ dysfunctions whose pathophysiology is not fully understood. Early intervention in sepsis is crucial for patient outcome, yet those interventions have adverse effects and are frequently overadministered.
arxiv  

Septic Shock [PDF]

open access: yes, 2016
Sepsis is a frequently seen diagnosis in hospital settings, which when left untreated can progress to severe sepsis and septic shock. Septic shock occurs in more than 230,000 patients in the United States annually and is the cause of more than 40,000 ...
Lauer, Lacey
core   +2 more sources

Trial of early, goal-directed resuscitation for septic shock.

open access: yesNew England Journal of Medicine, 2015
BACKGROUND Early, goal-directed therapy (EGDT) is recommended in international guidelines for the resuscitation of patients presenting with early septic shock.
P. Mouncey   +14 more
semanticscholar   +1 more source

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

open access: yesAdvanced Functional Materials, EarlyView.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong   +7 more
wiley   +1 more source

Perioperative optimization of Crohn's disease

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 10-26, January 2023., 2023
Most Crohn's disease patients require surgery during the course of their illness, especially those who experience complications. The management of perioperative medications and surgery‐related decision‐making should be individualized and patient‐centered based on a multidisciplinary approach.
Chun‐Chi Lin   +10 more
wiley   +1 more source

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

open access: yesIntensive Care Medicine, 2021
Laura Evans   +59 more
semanticscholar   +2 more sources

Septic Shock

open access: yesActa Clinica Belgica, 1975
Abstract The problems associated with septic shock are highlighted, including those which arose during a 3-year prospective study. Mortality in the first year of the study was 71 per cent, falling to 38 per cent in the third year. The reasons, for this fall are detailed. The pattern of survival times changed over the 3 years, giving rise
openaire   +4 more sources

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