Results 81 to 90 of about 609,887 (206)

MicroRNA-203 Acts as a Potent Suppressor in Septic Shock by Alleviating Lung Injury via Inhibition of VNN1

Kidney & Blood Pressure Research, 2019
Background: Septic shock, the most serious complication of sepsis, is a life-threatening disease that is mainly characterized by hypoperfusion and multiple organ failure. Various aberrantly expressed microRNAs (miRNAs) have been reported to be related to
Lan Ling, Hai-Tao Lu, Hai-Feng Wang, Mei-Jia Shen, Hong-Bo Zhang   +4 more
doaj   +1 more source

Phenoxybenzamine in Septic Shock

Annals of Surgery, 1967
Abstract : A series of young patients with well defined diagnoses and refractory clinical shock were studied hemodynamically. When conventional methods of therapy failed to correct hemodynamic deficits phenoxybenzamine was administered and physiologic parameters were carefully monitored.
R W, Anderson, P M, James, C E, Bredenberg, R M, Hardaway   +3 more
openaire   +3 more sources

Oxygen transport and mitochondrial function in porcine septic shock, cardiogenic shock, and hypoxaemia

, 2012
The relevance of tissue oxygenation in the pathogenesis of organ dysfunction during sepsis is controversial. We compared oxygen transport, lactate metabolism, and mitochondrial function in pigs with septic shock, cardiogenic shock, or hypoxic ...
Brandt, S, Borotto, E, Bracht, H, Jakob, S M, Gorrasi, J, Porta, F, Takala, J, Djafarzadeh, S, Regueira, T, Shaw, S, Lepper, P M   +10 more
core   +1 more source

Noninvasive ventilation failure in patients with hypoxemic respiratory failure: the role of sepsis and septic shock

Therapeutic Advances in Respiratory Disease, 2019
Background: Sepsis and septic shock are common in noninvasive ventilation (NIV) patients. However, studies on the association between sepsis and NIV failure are lacking.
Jun Duan, Lijuan Chen, Guopeng Liang, Weiwei Shu, Liucun Li, Ke Wang, Shengyu Wang, Xiaoyi Liu, Chunfeng He, Dehua He, Qimin Chen, Bilin Wei, Baixu Chen, Yuzhen Shu, Yao Tian, Liping Fan, Xiaoli Han, Rui Zhang, Xiangmei Yang, Yan Peng, Dong Wan, Xiaoying Chen, Lin Ye, Shijing Tian, Qiong Huang, Lei Jiang, Linfu Bai, Lintong Zhou   +27 more
doaj   +1 more source

Identification of cuproptosis-related genes in septic shock based on bioinformatic analysis.

PLoS ONE
BackgroundSeptic shock is a life-threatening condition characterized by a failure of organ systems and a high mortality rate. Cuproptosis is a new form of cell death that is triggered by copper overload.
Jintong Zhao, Meng Zhang, Ying Wang, Feifei He, Qiang Zhang   +4 more
doaj   +1 more source

Extracellular vesicle-bound S100A8/A9 is differentially expressed in septic shock and prompts acute lung injury

Respiratory Research
Background Sepsis is a common indirect insult leading to acute respiratory distress syndrome (ARDS). Circulating extracellular vesicles (EVs) have been reported to participate in the pathogenesis of sepsis.
Jiangmei Wang, Weiliang Wu, Tingting Wen, Guoping Zheng, Guanguan Qiu, Huifeng Qian, Ruoyang Zhang, Jie Xia, Yaoqin Hu, Ruoqiong Huang, Ruoxi Zang, Zhenkai Le, Qiang Shu, Jianguo Xu   +13 more
doaj   +1 more source

Septic shock and the lysosomal-mitochondrial axis theory of apoptosis

, 2009
Over 250 years ago, Le Dran, a distinguished French Surgeon, first used the word “shock” in his treatise. Since then, much progress has been made in shock research. However, many questions have still confused the medical doctors until now.
Brunk, Ulf,, Zhao, Ming,
core  

Identify value of rate pressure product in children with compensatory septic shock

European Journal of Medical Research
Background Septic shock is a major cause of mortality and is often difficult to recognize timely in pediatric patients. Rate pressure product (RPP) strongly correlates with oxygen consumption and is an indicator of the heart’s workload.
Haiyan Ge, Dong Qu, Chengdong Yu, Shuang Liu, Jin Zhang   +4 more
doaj   +1 more source

Association of metformin administration after septic shock with short-term and long-term survival in septic shock patients with diabetes

Annals of Intensive Care
Background In addition to glycemic control, the anti-inflammatory effects and protective effect of metformin on sepsis have been reported in animal studies, which may be beneficial for patients with septic shock.
Bo-Yeong Jin, Sukyo Lee, Woosik Kim, Jong-Hak Park, Hanjin Cho, Sungwoo Moon, Sejoong Ahn   +6 more
doaj   +1 more source

An ovine septic shock model of live bacterial infusion

Background: Escherichia coli is the most common cause of human bloodstream infections and bacterial sepsis/septic shock. However, translation of preclinical septic shock resuscitative therapies remains limited mainly due to low-fidelity of available ...
Obonyo, NG, Palmieri, C, Wilson, ES, Gandini, L, Bouquet, M, Farah, SM, Sato, K, Raman, S, Liu, K, Suen, JY, Passmore, MR, Hyslop, K, White, N, Phan, MD, et al., Peters, KM   +15 more
core   +1 more source