Results 61 to 70 of about 148,562 (307)

The Prevalence and Significance of Overt Disseminated Intravascular Coagulation in Patients with Septic Shock in the Emergency Department According to the Third International Consensus Definition [PDF]

Korean Journal of Critical Care Medicine, 2016
Background The prevalence and prognostic value of overt disseminated intravascular coagulation (DIC) in patients with septic shock presenting to emergency departments (EDs) is poorly understood, particularly following the release of a new definition of ...
Byuk Sung Ko, Hyun Young Cho, Seung Mok Ryoo, Myung Chun Kim, Woong Jung, Sung Hyuk Park, Chang Min Lee, Won Young Kim   +7 more
doaj   +1 more source

Cutoff Values of Hemodynamic Parameters in Pediatric Refractory Septic Shock

Children, 2022
Background: Refractory septic shock can cause severe morbidities and mortalities in children. Resuscitation based on hemodynamics is important in children with critical illness.
En-Pei Lee, Jainn-Jim Lin, Shao-Hsuan Hsia, Oi-Wa Chan, Sheng-Ling Jan, Han-Ping Wu   +5 more
doaj   +1 more source

Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood

, 2007
Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann, Matthias, Christoph Sucker, Zacharowski, Kai, Hartmann, Matthias, Kai Zacharowski, Matthias Thielmann, Sucker, Christoph, Sucker Christoph, Thielmann Matthias, Matthias Hartmann, Zacharowski Kai, Hartmann Matthias   +11 more
core   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Microbiological and Clinical Characteristics of Pediatric Sepsis Patients with and without Septic Shock: A Retrospective Study at a Tertiary Pediatric Hospital in China

Children
Background: Pediatric sepsis, a life-threatening condition, often progresses to septic shock. However, microbiological and clinical profiles between pediatric sepsis patients with and without septic shock remain underexplored. Methods: This retrospective
Kai-Cheng Peng, Qin-Yuan Li, Lin Chen, Yan Zhao, Hui Liu, Zhen-Xuan Kong, Zheng-Xiu Luo   +6 more
doaj   +1 more source

Diagnostic and Prognostic Significance of the Prothrombin Time/International Normalized Ratio in Sepsis and Septic Shock

Clinical and Applied Thrombosis/Hemostasis, 2022
Objective The study investigates the diagnostic and prognostic significance of the prothrombin time/international normalized ratio (PT/INR) in patients with sepsis and septic shock.
Tobias Schupp MD, Kathrin Weidner MD, Jonas Rusnak MD, Schanas Jawhar MS, Jan Forner MS, Floriana Dulatahu MS, Lea Marie Brück MS, Ursula Hoffmann MD, Thomas Bertsch MD, Julian Müller MD, Christel Weiß PhD, Ibrahim Akin MD, Michael Behnes MD   +12 more
doaj   +1 more source

The Neuropathology of Septic Shock

Brain Pathology, 2004
The neuropathological correlates of encephalopathy and autonomic dysfuction in septic shock are unclear. We performed post mortem analysis of 5 brain areas susceptible to ischemia and 5 autonomic nuclei (AN) in 23 pqtients who had died in our intensive care unit (ICU) from septic shock and 8 dying from non‐septic shock as well as 5 controls who had ...
Tarek, Sharshar, Djillali, Annane, Geoffroy Lorin, de la Grandmaison, Jean Philippe, Brouland, Nicholas S, Hopkinson, Gray, Françoise   +5 more
openaire   +3 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

EARLY GOAL-DIRECTED THERAPY IN TREATMENT OF PEDIATRIC SEPTIC SHOCK

, 2010
In the whole world, around 29,000 children younger than 5 years die every day, and sepsis is the most common cause of death. Whereas in adult patients vasomotor paralysis represents the predominant cause of mortality, death in pediatric sepsis is ...
OLIVEIRA, Claudio Flauzino de, Cláudio Flauzino de Oliveira   +1 more
core   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source