Results 61 to 70 of about 227,863 (293)

The Prevalence and Significance of Overt Disseminated Intravascular Coagulation in Patients with Septic Shock in the Emergency Department According to the Third International Consensus Definition [PDF]

Korean Journal of Critical Care Medicine, 2016
Background The prevalence and prognostic value of overt disseminated intravascular coagulation (DIC) in patients with septic shock presenting to emergency departments (EDs) is poorly understood, particularly following the release of a new definition of ...
Byuk Sung Ko, Hyun Young Cho, Seung Mok Ryoo, Myung Chun Kim, Woong Jung, Sung Hyuk Park, Chang Min Lee, Won Young Kim   +7 more
doaj   +1 more source

Cutoff Values of Hemodynamic Parameters in Pediatric Refractory Septic Shock

Children, 2022
Background: Refractory septic shock can cause severe morbidities and mortalities in children. Resuscitation based on hemodynamics is important in children with critical illness.
En-Pei Lee, Jainn-Jim Lin, Shao-Hsuan Hsia, Oi-Wa Chan, Sheng-Ling Jan, Han-Ping Wu   +5 more
doaj   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Management and Outcome of Severe Sepsis and Septic Shock Patients

Journal of Nepal Health Research Council, 2018
Background: Severe sepsis and septic shock are major causes of morbidity and mortality worldwide and need immediate medical attention. Early recognition, fluid resuscitation and early antimicrobials are the mainstays of sepsis therapy.
Sabitri Lamichhane, Nayan Manandhar, Shailendra Dhakal, Yagya Laxmi Shakya   +3 more
doaj   +1 more source

Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study [PDF]

, 2018
Background: Adrenomedullin (ADM) regulates vascular tone and endothelial permeability during sepsis. Levels of circulating biologically active ADM (bio-ADM) show an inverse relationship with blood pressure and a direct relationship with vasopressor ...
Abroug, S., Alcourt, Y., Allam, H., Antonelli, M., Aubrey, A., Bachoumas, K., Bangert, K., Barthelemy, R., Bartoli, C., Baudrillart, L., Bayer, S., Beeken, T., Beeker, T., Begot, E., Beishuizen, A., Beishuizen, B., Berghe, C., Bergmann, A., Berquier, G., Besancenot, H., Blet, A., Bloos, F., Bloos, P., Bodet-Contentin, L., Boivin, A., Bongiovanni, C., Bonnet, F., Border, N., Bos-Burgmeijer, M., Bouadma, L., Bouhours, G., Bourdier, J., Bourzeix, P., Braad, A., Brick, L., Brulls, C., Buelens, I., Calvat, S., Caumon, E., Cayot, S., Chapellas, C., Chassier, C., Chenaf, S., Chousterman, B. G., Clere-Jehl, R., Colin, G., Collienne, C., Constantin, J. -M., Conte, M., Cornet, A., Cracco, C., Cupaciu, A., Cutuli, S. L., D'Arrigo, S., Daix, T., Damoisel, C., De Heer, G., De Schryver, N., Deiler, V., Deisz, R., Delabranche, X., Delmas, J., Denou, F., Dequin, P. F., Desachy, A., Deschamps, A., Deye, N., Dhif, N., Di Somma, S., Digravio, V., Dubief, E., Duchambon, A. -A., Dugernier, T., Dujardin, M. -F., Ehrmann, S., Fally, M. A., Fedou, A. -L., Feld, F., Feliot, E., Fesard, P., Fiancette, M., Fournier, M. -C., Francois, B., Freys, G., Frings, D., Fuhrmann, V., Fullekrug, B., Gaillard, T., Galy, A., Garcon, P., Garot, D., Gaudry, S., Gaugain, S., Gayat, E., Geukens, P., Geven, C., Godet, T., Gonnert, F., Gouhier, C., Goury, A., Guerin, R., Guillon, A., Guyon, M., Hartmann, O., Haucke, A., Hecketsweiler, S., Heenen, S., Hemelaar, P., Henin, P., Henker, R., Henry-Lagarrigue, M., Herafa, I., Heunks, L., Hoedemaekers, A., Hohn, A., Hollinger, A., Huberlant, V., Huot, B., Jabaudon, M., Jacob, L., Janisch, T., Jaschinski, U., Joret, A., Jouan, Y., Kehl, L., Kelly, D. S., Kerdjana, L., Kerinn, M., Kerymel, M., Kluge, S., Kohlberg, K. K., Kolanos, S., Kortgen, A., Kreuser, I., Kummerlen, C., La Combe, B., La Foucher, B., Lacherade, J. -C., Lafon, C., Laissi, M., Laleu, S., Lascarrou, J. -B., Lascarrou, J. B., Lasocki, S., Laterre, P. -F., Laterre, P. F., Launoy, A., Laurent, Y., Lebert, C., Leblanc, D., Lebreton, S., Legall, C., Legrand, M., Legras, A., Lematte, M., Leone, F. E., Lessinger, J. -M., Letrou, S., Lindau, S., Loiez, A., Louadah, B., Lucht, A., Ludes, P. O., Mabilat, C., Magalhaes, E., Mairesse, J., Malissin, I., Mancia, C., Manivet, P., Maquigneau, N., Martin-Levevre, L., Marx, G., Marx, N., Massat, S., Mebazaa, A., Megarbane, B., Meier, B., Meier-Hellmann, A., Meinig, T., Mercier, E., Messika, J., Metzger, C., Meybohm, P., Meyer, A., Meziani, F., Mourvillier, B., Muller, J., Mutlak, H., Navarin, S., Neuville, M., Nierhaus, A., Nouaille, M., Orru, M., Oueslati, H., Papendorp, S., Pascal, J., Perbet, S., Petre, H., Pezechk, J., Pichon, N., Pickkers, P., Pierre, V., Pottecher, J., Quatrocchi, D., Quattrochi, D., Rabouel, Y., Radji, S., Radjou, A., Rahmani, H., Reignier, J., Renard, S., Ricard, J. -D., Ringeis, G., Rinket, M., Robert, A., Robin, L., Rodier, N., Rolhion, C., Rommer, M., Roovers, N., Roszyk, L., Rouleau, S., Rousseau, C., Rouve, E., Roux, D., Ruimy, A., Russo, V., Salmon, C., Schedler, D., Schindler, A., Schnell, D., Schreiber, J., Schroder, D., Schuerholz, T., Schwope, K., Scigalla, P., Sebastien, L., Sensen, B., Siedler, S., Siewecke, A., Simeon-Vieules, V., Simon, T. -P., Simona, S., Singer, B., Soffker, G., Sonneville, R., Soyer, B., Struck, J., Szozot, M., Thibault, S., Thirifays, A., Thomas-Ruddel, D., Timsit, J. -F., Trine, H., Trof, R. J., Vallecoccia, M. S., Van Der Hoeven, H., Van Wezel, H., Varchetta, A., Verlhac, C., Vermeijden, J., Victori, G., Vignon, P., Vinatier, I., Vinetti, M., Voicu, S., Wetsch, W., Wichmann, D., Wittebole, X., Yehia, A., Zacharowski, K. D., Zanquila, M., Zapatero, D. C., Zinzonni, V. E., Zoccoli, G.   +274 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Microbiological and Clinical Characteristics of Pediatric Sepsis Patients with and without Septic Shock: A Retrospective Study at a Tertiary Pediatric Hospital in China

Children
Background: Pediatric sepsis, a life-threatening condition, often progresses to septic shock. However, microbiological and clinical profiles between pediatric sepsis patients with and without septic shock remain underexplored. Methods: This retrospective
Kai-Cheng Peng, Qin-Yuan Li, Lin Chen, Yan Zhao, Hui Liu, Zhen-Xuan Kong, Zheng-Xiu Luo   +6 more
doaj   +1 more source

Diagnostic and Prognostic Significance of the Prothrombin Time/International Normalized Ratio in Sepsis and Septic Shock

Clinical and Applied Thrombosis/Hemostasis, 2022
Objective The study investigates the diagnostic and prognostic significance of the prothrombin time/international normalized ratio (PT/INR) in patients with sepsis and septic shock.
Tobias Schupp MD, Kathrin Weidner MD, Jonas Rusnak MD, Schanas Jawhar MS, Jan Forner MS, Floriana Dulatahu MS, Lea Marie Brück MS, Ursula Hoffmann MD, Thomas Bertsch MD, Julian Müller MD, Christel Weiß PhD, Ibrahim Akin MD, Michael Behnes MD   +12 more
doaj   +1 more source

High‐Resolution and Real‐Time In Situ Generation of Cellular Spheroids by Laser‐Assisted Bioprinting for Guided Microvascularization

Advanced Functional Materials, EarlyView.
Micro‐injection laser‐assisted bioprinting enables ultrafast and precise patterning of small endothelial cell spheroids by injecting a highly concentrated single‐cell suspension into GelMA/ColMA hydrogels. In co‐culture with fibroblasts, controlled pre‐vasculogenic network formation is obtained at microscale resolution.
Charles Handschin, Katharina Wulz, Clotilde Jugie, Marie‐Laure Stachowicz, Shane Fennell, Aurélien Mazet, Malou Lea, Nathalie Dusserre, Jean‐Christophe Fricain, Hugo Oliveira   +9 more
wiley   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

Advanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee, Stefanie S. M. Meier, Sara Trujillo, Andreas Möglich, Shrikrishnan Sankaran   +4 more
wiley   +1 more source