Results 51 to 60 of about 609,887 (206)

Translational gap in pediatric septic shock management: an ESPNIC perspective [PDF]

, 2019
Background: The Surviving Sepsis Campaign and the American College of Critical Care Medicine guidelines have provided recommendations for the management of pediatric septic shock patients.
ESPNIC Refractory Septic Shock Definition taskforce and the Infe, Kneyber, M, Morin, L, Schlapbach, LJ, Jansen, NJG, Maclaren, G, Peters, MJ, Nadel, S, Tissieres, P, Javouhey, E   +9 more
core   +3 more sources

Management of Septic Shock

Annals of Medicine, 2002
Severe sepsis is a common disease process affecting some 2-11% of hospital admissions in the US. Severe sepsis and septic shock are associated with considerable morbidity and mortality, and account for a large part of intensive care unit costs.
Vincent, Jean Louis, Bruzzi de Carvalho, Frederico, De Backer, Daniel   +2 more
openaire   +3 more sources

Novel potential therapies for septic shock

, 2008
Sepsis is the systemic inflammatory response syndrome secondary to a local infection. Septic shock, the severe complication of sepsis associated with refractory hypotension, is frequently a near-fatal condition requiring prompt diagnosis and management ...
PARK, Marcelo, SCHETTINO, Guilherme Paula Pinto, AZEVEDO, Luciano Cesar Pontes   +2 more
core   +1 more source

Sepsis and septic shock [PDF]

Nature Reviews Disease Primers, 2016
For more than two decades, sepsis was defined as a microbial infection that produces fever (or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now increasingly being considered a dysregulated systemic inflammatory and immune response to microbial invasion that produces organ injury for which mortality rates are declining to
Hotchkiss, Richard R.S., Moldawer, Lyle Linc, Opal, Steven, Reinhart, Konrad, Turnbull, Isaiah I.R., Vincent, Jean Louis   +5 more
openaire   +5 more sources

Staphylococcus schleiferi subspecies coagulans septic shock in an immunocompetent male following canine otitis externa

, 2023
Staphylococcus schleiferi bacteremia is an underappreciated cause of septic shock in the critical care department. Although nominally a coagulase variable Staphylococcus and associated with otitis externa infections in canine species, it has been ...
Deborah Moran, Moran, D, Eland, CL, AndrewDK Nguyen, Kathryn Wilks, Wilks, K, Carole-Lynn Eland, Nguyen, A   +7 more
core   +1 more source

INCREASED LEVELS OF GLYCOSAMINOGLYCANS DURING SEPTIC SHOCK: RELATION TO MORTALITY AND THE ANTIBACTERIAL ACTIONS OF PLASMA.

, 2008
Glycosaminoglycans (GAGs) are structurally heterogeneous negatively charged polysaccharides. Endothelial GAGs, also known as glycocalyx, are involved in capillary permeability.
Bodelsson, Mikael, Nelson, Axel, Berkstedt, Ingrid, Berkestedt, Ingrid, Schmidtchen, Artur, Ljunggren, Lennart,, Ljunggren, Lennart   +6 more
core   +2 more sources

Soluble CD25 as a potential prognostic biomarker for pediatric septic shock and its comparison with hemophagocytic lymphohistiocytosis

BMC Research Notes
Objectives Identifying children at highest risk for deterioration during evaluation for septic shock in emergency department (ED) settings remains challenging.
T. B. Garcia, V. Knight, H. F. Scott
doaj   +1 more source

Prevalence and Management of Septic Shock among Children Admitted at the Kenyatta National Hospital, Longitudinal Survey

International Journal of Pediatrics, 2019
Background. Paediatric septic shock is a subset of sepsis associated with high mortality. Implementing the existing international Surviving Sepsis Campaign Guidelines 2012 (SSCG) have contributed to reduction of mortality in many places but these have ...
Varsha Vekaria-Hirani, Rashmi Kumar, Rachel N. Musoke, Ezekiel M. Wafula, Idris N. Chipkophe   +4 more
doaj   +1 more source

Association of annual hospital septic shock case volume and hospital mortality

Critical Care, 2022
Background The burden of sepsis remains high in China. The relationship between case volume and hospital mortality among patients with septic shock, the most severe complication of sepsis, is unknown in China.
Yan Chen, Xu-dong Ma, Xiao-hui Kang, Si-fa Gao, Jin-min Peng, Shan Li, Da-wei Liu, Xiang Zhou, Li Weng, Bin Du, China National Critical Care Quality Control Center Group   +10 more
doaj   +1 more source

Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock

Critical Care, 2018
Background Renal perfusion status remains poorly studied at the bedside during septic shock. We sought to measure cortical renal perfusion in patients with septic shock during their first 3 days of care using renal contrast enhanced ultrasound (CEUS ...
Anatole Harrois, Nicolas Grillot, Samy Figueiredo, Jacques Duranteau   +3 more
doaj   +1 more source