The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability [PDF]
, 2008 Introduction The purpose of this study was to assess the relation between glycaemic control and the severity of sepsis in a cohort of patients treated with intensive insulin therapy (IIT).
Michael Quintel +5 more
core +2 more sources
Clinical solutions: not always what they seem? [PDF]
, 2015 Brenner and colleagues, in their article published in Critical Care, showed elevated levels of the reactive carbonyl species (RCS) methylglyoxal (MG) in the circulation of patients with septic shock.
Burke-Gaffney, A, Creagh-Brown, BC
core +3 more sources
An overview of the mechanisms and potential roles of extracellular vesicles in septic shock
Frontiers in ImmunologySeptic shock, a subset of sepsis, is a fatal condition associated with high morbidity and mortality. However, the pathophysiology of septic shock is not fully understood. Moreover, the diagnostic markers employed for identifying septic shock lack optimal
Meiling Cao +3 more
doaj +1 more source
Hereditas, 2021 Background Sepsis and septic shock are life-threatening diseases with high mortality rate in intensive care unit (ICU). Acute kidney injury (AKI) is a common complication of sepsis, and its occurrence is a poor prognostic sign to septic patients.
Yun Tang +6 more
doaj +1 more source
Fluid balance and cardiac function in septic shock as predictors of hospital mortality [PDF]
, 2013 INTRODUCTION: Septic shock is a major cause of morbidity and mortality throughout the world. Unfortunately, the optimal fluid management of septic shock is unknown and currently is empirical.
Doherty, Joshua A +5 more
core +3 more sources
CD63 and C3AR1: The Potential Molecular Targets in the Progression of Septic Shock
International Journal of General Medicine, 2022 Ning Yu, Xuefang Liu, Dandan Shi, Long Bai, Tianfu Niu, Ya Liu Department of Anaesthesiology and Intensive Care, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050004, People’s Republic of ChinaCorrespondence: Ya Liu,
Yu N, Liu X, Shi D, Bai L, Niu T, Liu Y
doaj
A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]
, 2012 Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J +2 more
core +2 more sources
The effect of goal-directed therapy on mortality in patients with sepsis - earlier is better: A meta-analysis of randomized controlled trials [PDF]
, 2014 __Introduction:__ The Surviving Sepsis Campaign guidelines recommend goal-directed therapy (GDT) for the early resuscitation of patients with sepsis. However, the findings of the ProCESS (Protocolized Care for Early Septic Shock) trial showed no benefit ...
Bakker, J. (Jan) +4 more
core +4 more sources
Specific Removal of Monocytes from Peripheral Blood of Septic Patients by Polymyxin B-immobilized Filter Column [PDF]
, 2009 Lipopolysaccharide (LPS) is one of the major causes of septic shock. The polymyxin B-immobilized filter column (PMX) was developed for the adsorption of endotoxin by direct hemoperfusion and has been used for the treatment of LPS-induced septic shock. In
Iwagaki, Hiromi +8 more
core +1 more source
Annals of Intensive Care, 2021 Background Baseline characteristics and disease severity of patients with septic shock according to the new Sepsis-3 definition may differ from patients that only comply with the Sepsis-2 definition.
Joris Vermassen +4 more
doaj +1 more source