Акушерство, гинекология и репродукция, 2020 The problem of sepsis and septic shock has recently become more and more actual. In obstetrics and gynaecology, the number of cases of sepsis has more than doubled over the past 10 years.
V. O. Bitsadze +13 more
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Critical Care Clinics, 1997 Although our understanding of molecular events in septic shock is growing exponentially, bedside management has changed only incrementally over the last 20 years. In pediatric and adult patients alike, treatment continues to be largely supportive. Morbidity and mortality, though gradually improving, continue to be high.
J A, Carcillo, R E, Cunnion
openaire +4 more sources
The Weekend Effect in Septic Shock Patients Using the Nationwide Emergency Department Sample Database [PDF]
, 2021 Background:The weekend effect is the increased mortality in hospitalized patients admitted on the weekend. The aim of this study was to examine the effect of weekend admissions on septic shock patients.Methods:This is a retrospective observational study ...
Bou Chebl, Ralph +15 more
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The interaction of vasopressin and corticosteroids in septic shock: a pilot randomized controlled trial. [PDF]
, 2014 OBJECTIVES: Vasopressin and corticosteroids are both commonly used adjunctive therapies in septic shock. Retrospective analyses have suggested that there may be an interaction between these drugs, with higher circulating vasopressin levels and improved ...
Terblanche, Marius +17 more
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Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]
, 2005 Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Briegel, Josef +4 more
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Protocol for a randomised controlled trial of VAsopressin versus Noradrenaline as Initial therapy in Septic sHock (VANISH). [PDF]
, 2014 INTRODUCTION: Vasopressin is an alternative vasopressor in the management of septic shock. It spares catecholamine use but whether it improves outcome remains uncertain.
Brett, Stephen J. +13 more
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The effects of hypertonic fluid administration on the gene expression of inflammatory mediators in circulating leucocytes in patients with septic shock: a preliminary study [PDF]
, 2011 Contains fulltext : 98426.pdf (Publisher’s version ) (Open Access)ABSTRACT: OBJECTIVE: This study was designed to investigate the effect of hypertonic fluid administration on inflammatory mediator gene expression in patients with septic
James Sleigh +17 more
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Topical issues of clinical symptoms and diagnostics of septic shock
Инфекция и иммунитет, 2022 Currently, septic shock remains an unresolved public health problem that leads to serious epidemiological, economic and social problems. Septic shock is a common hemodynamic disorder caused by the interaction between pathogenic microbes and host cells ...
Liliya I. Gomanova, Marina A. Fokina
doaj +1 more source
4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study. [PDF]
, 2010 In Caucasian patients with severe sepsis due to pneumonia carriers of the 4G allele of PAI-1 polymorphism have higher risk for multiple organ dysfunction syndrome and septic shock and in agreement they showed more fulminant disease progression based on ...
Aladzsity, István +20 more
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A model of porcine polymicrobial septic shock
Intensive Care Medicine Experimental, 2023 Background Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality of patients with sepsis is high and largely unchanged throughout the past decades.
Finnja Marie Zurek-Leffers +12 more
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