Results 151 to 160 of about 997,918 (264)

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock

New England Journal of Medicine, 2018
D. Annane, A. Renault, C. Brun-Buisson, B. Mégarbane, J. Quenot, S. Siami, A. Cariou, X. Forceville, C. Schwebel, Claude D Martin, J. Timsit, B. Misset, M. Benali, G. Colin, B. Souweine, K. Asehnoune, E. Mercier, L. Chimot, C. Charpentier, B. François, T. Boulain, F. Petitpas, J. Constantin, G. Dhonneur, F. Baudin, A. Combes, J. Bohé, J. Loriferne, R. Amathieu, F. Cook, M. Slama, O. Leroy, G. Capellier, A. Dargent, T. Hissem, V. Maxime, É. Bellissant   +36 more
semanticscholar   +1 more source

The Circadian Transcription Factor CLOCK Modulates Oxidative Stress Resistance via the ACHL–Relish Axis in Drosophila

Advanced Science, EarlyView.
This study identifies the circadian transcription factor CLOCK (CLK) as a key regulator of oxidative stress resistance in fruit flies. CLK controls immune responses by driving rhythmic transcription of an RNA‐binding protein‐Achilles (ACHL) in the fly brain, which post‐transcriptionally represses the NF‐κB homolog Relish, limiting immune activation and
Xu Liu, Jiajia Fang, Dawei Cheng, Wei Luan, Yan Lv, Wen Hu, Lei Pan, Yong Zhang   +7 more
wiley   +1 more source

Gastrointestinal function and nutritional interventions in septic shock. [PDF]

Curr Opin Crit Care
Bachmann KF, Cotoia A, Reintam Blaser A.
europepmc   +1 more source

A Multicentre Study of Acute Kidney Injury in Severe Sepsis and Septic Shock: Association with Inflammatory Phenotype and HLA Genotype

, 2012
Didier Payen, Anne‐Claire Lukaszewicz, Matthieu Legrand, Étienne Gayat, Valérie Faivre, Bruno Mégarbane, Élie Azoulay, Fabienne Fieux, Dominique Charron, Pascale Loiseau, Marc Busson   +10 more
openalex   +2 more sources

A randomized trial of protocol-based care for early septic shock.

New England Journal of Medicine, 2014
D. Yealy, J. Kellum, David T. Huang, A. Barnato, L. Weissfeld, F. Pike, T. Terndrup, HE Wang, P. Hou, F. LoVecchio, M. Filbin, N. Shapiro, D. Angus   +12 more
semanticscholar   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

Advanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu, Xuechun Yu, Yanling Li, Lin An, Rongrong Zhang, Rong Zhang, Fan Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

Racial and ethnic differences in COVID-19-associated septic shock. [PDF]

World J Crit Care Med
Ang SP, Chia JE, Lorenzo-Capps MJ, Lee E, Iglesias J.   +4 more
europepmc   +1 more source

Adjunctive Glucocorticoid Therapy in Patients with Septic Shock

New England Journal of Medicine, 2018
B. Venkatesh, S. Finfer, Jeremy Cohen, D. Rajbhandari, Y. Arabi, R. Bellomo, L. Billot, Maryam Correa, P. Glass, M. Harward, C. Joyce, Qiang Li, C. McArthur, A. Perner, A. Rhodes, Kelly J Thompson, S. Webb, J. Myburgh   +17 more
semanticscholar   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

Advanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li, Weijia Chen, Mengxue Sun, Xinbo Ni, Qishan Ran, Xiaoyu Hu, Fang Cao, Wenwen Zeng   +7 more
wiley   +1 more source

Risk factors for chronic kidney disease and septic shock with hypertension in adults and children. [PDF]

Front Nephrol
Javier RM, Salim J, Aji BL, Pradipta BPA, Nur C, Muhammad I, Aflah LN, Rettauli IAB, Audrey C, Wijayaningtyas I, Kosen YD, Fajriyadi A, Sabila N, Salipadang FP, Nugraha MA, Cheda NY, Putra APY, Mahasin DF, Subiyanto MD, Berlian AZ, Hadiaturahman MZ, Luthfi RK, Aditya MR, Arif HC, Kurniawan K.   +24 more
europepmc   +1 more source