Results 151 to 160 of about 1,083,142 (408)

Septic Shock in Pyogenic Liver Abscess: Clinical Considerations

The Korean Journal of Gastroenterology, 2016
Background : /Aims: Pyogenic liver abscess (PLA) is a life-threatening condition, despite advances in diagnostic technology and strategies for treatment. A strong predictor of mortality in this condition is septic shock.
A Reum Cho, Tae Hee Lee, Min Ji Park, Sun Hee Oh, Joo Ah Lee, Joo Ho Park, Ki Hyun Ryu, Hoon Sup Koo, Kyung Ho Song, Sun Moon Kim, Kyu Chan Huh, Young Woo Choi, Young Woo Kang   +12 more
doaj   +1 more source

Circulating microparticles from septic shock patients exert differential tissue expression of enzymes related to inflammation and oxidative stress [PDF]

, 2011
Objective: Septic shock is characterized by hypotension and multiple organ failure after infection of microorganisms. Septic shock patients display high levels of circulating microparticles.
F. Meziani, H.Ahmed Mostefai, M.C. Martinez, M.Letizia Mastronardi, P. Asfar, R. Andriantsitohaina   +5 more
core   +2 more sources

Current use of vasopressors in septic shock

Annals of Intensive Care, 2019
BackgroundVasopressors are commonly applied to restore and maintain blood pressure in patients with sepsis. We aimed to evaluate the current practice and therapeutic goals regarding vasopressor use in septic shock as a basis for future studies and to ...
Thomas W. L. Scheeren, J. Bakker, D. De Backer, D. Annane, P. Asfar, E. Boerma, M. Cecconi, A. Dubin, M. Dünser, J. Duranteau, Anthony C. Gordon, O. Hamzaoui, G. Hernández, M. Leone, B. Levy, Claude D Martin, A. Mebazaa, X. Monnet, A. Morelli, D. Payen, R. Pearse, M. Pinsky, P. Radermacher, D. Reuter, B. Saugel, Y. Sakr, M. Singer, P. Squara, A. Vieillard-Baron, P. Vignon, S. Vistisen, I. V. D. van der Horst, J. Vincent, J. Teboul   +33 more
semanticscholar   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

Automatic Detection of Coronavirus Disease (COVID-19) in X-ray and CT Images: A Machine Learning-Based Approach [PDF]

arXiv, 2020
The newly identified Coronavirus pneumonia, subsequently termed COVID-19, is highly transmittable and pathogenic with no clinically approved antiviral drug or vaccine available for treatment. The most common symptoms of COVID-19 are dry cough, sore throat, and fever.
arxiv  

Narrative review: clinical assessment of peripheral tissue perfusion in septic shock

Annals of Intensive Care, 2019
Sepsis is one of the main reasons for intensive care unit admission and is responsible for high morbidity and mortality. The usual hemodynamic targets for resuscitation of patients with septic shock use macro-hemodynamic parameters (hearth rate, mean ...
Geoffroy Hariri, J. Joffre, G. Leblanc, Michael Bonsey, J. Lavillegrand, T. Urbina, B. Guidet, É. Maury, J. Bakker, H. Ait-Oufella   +9 more
semanticscholar   +1 more source

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

Advanced Science, EarlyView.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao   +16 more
wiley   +1 more source

Identification of cuproptosis-related genes in septic shock based on bioinformatic analysis.

PLoS ONE
BackgroundSeptic shock is a life-threatening condition characterized by a failure of organ systems and a high mortality rate. Cuproptosis is a new form of cell death that is triggered by copper overload.
Jintong Zhao, Meng Zhang, Ying Wang, Feifei He, Qiang Zhang   +4 more
doaj   +1 more source

Fluid therapy and hemodynamic support in septic shock

Journal of Pediatric Critical Care, 2018
Sepsis remains one of the leading causes of mortality in children all over the world, especially in the developing nations. Early recognition of sepsis and septic shock facilitate the resuscitation, further reducing the morbidity and mortality related to
Milind Jambagi, Rakshay Shetty
doaj   +1 more source

Discrete Optimization for Interpretable Study Populations and Randomization Inference in an Observational Study of Severe Sepsis Mortality [PDF]

arXiv, 2014
Motivated by an observational study of the effect of hospital ward versus intensive care unit admission on severe sepsis mortality, we develop methods to address two common problems in observational studies: (1) when there is a lack of covariate overlap between the treated and control groups, how to define an interpretable study population wherein ...
arxiv