Results 161 to 170 of about 1,087,361 (389)

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

Decreased immunoreactivity and binding activity of corticosteroid-binding globulin in serum in septic shock. [PDF]

, 1989
M. Pugeat, AGNÉS BONNETON, D. Perrot, B Rocle-Nicolas, Hervé Lejeune, Catherine Grenot, H. Déchaud, C. Brébant, J Motin, Claude Y. Cuilleron   +9 more
openalex   +1 more source

Septic Shock

, 2018
For more than 20 years, sepsis has been defined as symptoms associated with the response to microorganism infection, which was more specifically called systemic inflammatory response syndrome (SIRS). With the evidence of organ failure, it was called severe sepsis, and this could lead to hypotension (septic shock).
Kim, Kyuseok, Choi, Han Sung, Chung, Sung Phil, Kwon, Woon Young   +3 more
openaire   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Extracellular phospholipase A2: causative agent in circulatory collapse of septic shock? [PDF]

, 1988
Peter Vadas, W. Pruzanski, E. Stefanski
openalex   +1 more source

Endothelin-1 and blood pressure after inhibition of nitric oxide synthesis in human septic shock [PDF]

, 1999
BACKGROUND: The systemic hypotension during human sepsis has been ascribed to increased production of nitric oxide (NO). Therefore, inhibitors of NO synthesis have been used in the treatment of hypotension in patients with
Avontuur, J.A.M., Boomsma, F. (Frans), Bruining, H.A. (Hajo), Jong, F.H. (Frank) de, Meiracker, A.H. (Anton) van den   +4 more
core  

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

Advanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen, Can Chen, Yichen Wu, Yinxue Xia, Ruijie Luo, Jiangcheng Shu, Long Chen, Zhaohui Wang, Cheng Wang, Kai Huang   +9 more
wiley   +1 more source

Predicting patients with septic shock and sepsis through analyzing whole-blood expression of NK cell-related hub genes using an advanced machine learning framework

Frontiers in Immunology
BackgroundSepsis is a life-threatening condition that causes millions of deaths globally each year. The need for biomarkers to predict the progression of sepsis to septic shock remains critical, with rapid, reliable methods still lacking. Transcriptomics
Chao Du, Chao Du, Chao Du, Stephanie C. Tan, Stephanie C. Tan, Heng-Fu Bu, Heng-Fu Bu, Saravanan Subramanian, Saravanan Subramanian, Hua Geng, Hua Geng, Xiao Wang, Xiao Wang, Hehuang Xie, Xiaowei Wu, Tingfa Zhou, Ruijin Liu, Zhen Xu, Bing Liu, Xiao-Di Tan, Xiao-Di Tan, Xiao-Di Tan   +21 more
doaj   +1 more source

The Comparison of Myocardial Dysfunction in Three Forms of Experimental Septic Shock [PDF]

, 1986
Keith J. Peevy, Tim Reed, Stephen A. Chartrand, Richard D. Olson, Robert C. Boerth   +4 more
openalex   +1 more source

Hyperglycaemia as a predictor of mortality and prolonged length of stay in severe sepsis and septic shock patients presented to red zone of emergency department, Hospital Universiti Sains Malaysia: a retrospective study [PDF]

, 2015
Introduction: Initial or at-admission hyperglycaemia is a risk marker of morbidity and mortality in many acute critical illnesses. There has been no study to evaluate hyperglycaemia in severe sepsis and septic shock in the emergency department setting.
Azil , Azlizawati
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