Results 171 to 180 of about 1,083,142 (408)
Data-driven discovery of a novel sepsis pre-shock state predicts impending septic shock in the ICU
Scientific Reports, 2019 Septic shock is a life-threatening condition in which timely treatment substantially reduces mortality. Reliable identification of patients with sepsis who are at elevated risk of developing septic shock therefore has the potential to save lives by ...
Ran Liu +6 more
semanticscholar +1 more source
The Neuropathology of Septic Shock
Brain Pathology, 2004 The neuropathological correlates of encephalopathy and autonomic dysfuction in septic shock are unclear. We performed post mortem analysis of 5 brain areas susceptible to ischemia and 5 autonomic nuclei (AN) in 23 pqtients who had died in our intensive care unit (ICU) from septic shock and 8 dying from non‐septic shock as well as 5 controls who had ...
Nicholas S Hopkinson +5 more
openaire +4 more sources
COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma
Advanced Science, EarlyView.COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo +15 more
wiley +1 more source
COVID‐19 in the Pacific territories: Isolation, borders and the complexities of governance
Asia &the Pacific Policy Studies, Volume 9, Issue 3, Page 394-407, September 2022., 2022 Abstract Early experience of COVID‐19 in seven Pacific politically dependent territories (Guam, American Samoa, Pitcairn, Tokelau, French Polynesia, Wallis and Futuna, and New Caledonia) emphasises a diversity of contexts, responses, outcomes and possible futures.
John Connell
wiley +1 more source
Reducing Mortality from Septic Shock Using an Interleukin-1 Receptor Antagonist [PDF]
, 2017 Septic shock, a severe inflammatory state secondary to a bacterial infection with refractory hypotension and tissue hypoperfusion despite adequate fluid resuscitation, is a leading cause of mortality in intensive care units worldwide.
Chung, Juyeon
core +1 more source
Journal of the American Medical Association (JAMA), 2016 IMPORTANCE Norepinephrine is currently recommended as the first-line vasopressor in septic shock; however, early vasopressin use has been proposed as an alternative.
A. Gordon +12 more
semanticscholar +1 more source
Advanced Science, EarlyView.Network‐based risk stratification of people living with HIV (PWH) on prolonged therapy using multi‐omics data identifies 44% of the patients are at risk of immunometabolic complications. A senescence‐associated myeloid cell‐driven plasma microenvironment drives immunometabolic dysregulation in at‐risk PWH.
Flora Mikaeloff +32 more
wiley +1 more source
A Septic with 99 real Nodes [PDF]
arXiv, 2004 We find a surface of degree 7 in real projective three-space P^3(R) with 99 real nodes within a family of surfaces with dihedral symmetry: First, we consider this family over some small prime fields, which allows us to test all possible parameter sets using computer algebra.
arxiv
HDAC6 Mediates Macrophage iNOS Expression and Excessive Nitric Oxide Production in the Blood During Endotoxemia [PDF]
, 2020 Excessive nitric oxide (NO) production and NO-mediated nitrative stress contribute to vascular dysfunction, inflammation, and tissue injury in septic shock.
Fu, Jian, Wang, Ke, Wang, Yan
core +1 more source
DECREASED DOPAMINE-BETA-HYDROXYLASE ACTIVITY IN SEPTIC SHOCK [PDF]
, 1979 A Harari +5 more
openalex +1 more source