Results 111 to 120 of about 1,296,938 (317)
webPRANK: a phylogeny-aware multiple sequence aligner with interactive alignment browser
BMC Bioinformatics, 2010 Background Phylogeny-aware progressive alignment has been found to perform well in phylogenetic alignment benchmarks and to produce superior alignments for the inference of selection on codon sequences.
Goldman Nick, Löytynoja Ari
doaj +1 more source
MAVID: Constrained ancestral alignment of multiple sequences [PDF]
arXiv, 2003 We describe a new global multiple alignment program capable of aligning a large number of genomic regions. Our progressive alignment approach incorporates the following ideas: maximum-likelihood inference of ancestral sequences, automatic guide-tree construction, protein based anchoring of ab-initio gene predictions, and constraints derived from a ...
arxiv
Global Network Alignment [PDF]
, 2010 Motivation: High-throughput methods for detecting molecular interactions have lead to a plethora of biological network data with much more yet to come, stimulating the development of techniques for biological network alignment.
Natasa Przulj, Oleksii Kuchaiev
core +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Alignment of protein-coding sequences with frameshift extension penalties [PDF]
arXiv, 2015 We introduce an algorithm for the alignment of protein- coding sequences accounting for frameshifts. The main specificity of this algorithm as compared to previously published protein-coding sequence alignment methods is the introduction of a penalty cost for frameshift ex- tensions.
arxiv
Molecular Oncology, EarlyView.PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang +6 more
wiley +1 more source
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal +5 more
wiley +1 more source
Efficient pairwise RNA structure prediction and alignment using sequence alignment constraints
BMC Bioinformatics, 2006 Background We are interested in the problem of predicting secondary structure for small sets of homologous RNAs, by incorporating limited comparative sequence information into an RNA folding model.
Dowell Robin D, Eddy Sean R
doaj +1 more source
Molecular Oncology, EarlyView.High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies +9 more
wiley +1 more source
Implementation of Basic Local Alignment Search for Detection H1N1 Sequence Alignment
International Journal of Trends in Mathematics Education Research, 2019 Bioinformatics is a science that studies the management and analysis of biological information. Bioinformatics includes application of mathematics, statistics, and informatics to biological problems to solve.
Retno Tri Vulandari +3 more
doaj +1 more source