DNA binding properties in vivo and target recognition domain sequence alignment analyses of wild-type and mutant RsrI [N6-adenine] DNA methyltransferases [PDF]
S. S. Szegedi
openalex +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
A measure of the similarity of sets of sequences not requiring sequence alignment.
B. Edwin Blaisdell
openalex +1 more source
TOPAL 2.0: improved detection of mosaic sequences within multiple alignments [PDF]
Gráinne McGuire, Frank Wright
openalex +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Web user segmentation using sequence alignment
Nowadays, with the rapid advances in e-commerce, user interest understanding becomes more and more essential in order to benefit the business.
Lưu Vĩnh Trung
doaj
Parallel DNA Sequence Alignment on High-Performance Systems with CUDA and MPI [PDF]
Sequence alignment is a cornerstone of bioinformatics, widely used to identify similarities between DNA, RNA, and protein sequences and studying evolutionary relationships and functional properties. The Needleman-Wunsch algorithm remains a robust and accurate method for global sequence alignment.
arxiv
An iterative method for faster sum-of-pairs multiple sequence alignment [PDF]
Knut Reinert, Jens Stoye, Torsten Will
openalex +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
The Practical Use of the A* Algorithm for Exact Multiple Sequence Alignment [PDF]
Martin Lermen, Knut Reinert
openalex +1 more source