A method for measuring spatial resolution based on clinical chest CT sequence images
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose This study aimed to develop and validate a method for characterizing the spatial resolution of clinical chest computed tomography (CT) sequence images. Methods An algorithm for characterizing spatial resolution based on clinical chest CT sequence images was developed in Matlab (2021b).
Ying Liu +3 more
wiley +1 more source
Exploring the Propensities of Helices in PrPC to Form β Sheet Using NMR Structures and Sequence Alignments [PDF]
, 2002 Ruxandra I. Dima, D. Thirumalai
openalex +1 more source
Definition of the tempo of sequence diversity across an alignment and automatic identification of sequence motifs: Application to protein homologous families and superfamilies [PDF]
, 2002 Alex C.W. May
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie +4 more
wiley +1 more source
Improving performance of multiple sequence alignment analysis in multi-client environments [PDF]
, 2002 Ümit V. Çatalyürek +4 more
openalex +1 more source
Relationship of cognitive decline with glucocerebrosidase activity and amyloid‐beta 42 in DLB and PD
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) share clinical, pathological, and genetic risk factors, including GBA1 and APOEε4 mutations. Biomarkers associated with the pathways of these mutations, such as glucocerebrosidase enzyme (GCase) activity and amyloid‐beta 42 (Aβ42) levels, may hold potential as predictive ...
Maria Camila Gonzalez +15 more
wiley +1 more source
Multiple sequence alignment using partial order graphs [PDF]
, 2002 Christopher Lee +2 more
openalex +1 more source
Heterozygous variants in AP4S1 are not associated with a neurological phenotype
Annals of Clinical and Translational Neurology, EarlyView.Abstract Biallelic loss‐of‐function variants in AP4S1 cause childhood‐onset hereditary spastic paraplegia. A recent report suggested that heterozygous AP4S1 variants lead to a syndrome of lower limb spasticity and dysregulation of sphincter function. We critically evaluate this claim against clinical observations in 28 heterozygous carriers of the same
Vicente Quiroz +9 more
wiley +1 more source
MGAlignIt: a web service for the alignment of mRNA/EST and genomic sequences [PDF]
, 2003 Bernett T.K. Lee +2 more
openalex +1 more source
Skin calcium deposits in primary familial brain calcification: A novel potential biomarker
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Primary Familial Brain Calcification (PFBC) is a rare neurodegenerative disorder characterized by small vessel calcifications in the basal ganglia. PFBC is caused by pathogenic variants in different genes and its physiopathology is still largely unknown. Skin vascular calcifications have been detected in single PFBC cases, suggesting
Aron Emmi +8 more
wiley +1 more source