DNA sequence analysis of SLC26A5, encoding prestin, in a patient-control cohort: identification of fourteen novel DNA sequence variations. [PDF]
Prestin, encoded by the gene SLC26A5, is a transmembrane protein of the cochlear outer hair cell (OHC). Prestin is required for the somatic electromotile activity of OHCs, which is absent in OHCs and causes severe hearing impairment in mice lacking ...
Jacob S Minor+3 more
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Copper Ions Induce DNA Sequence Variation in Zygotic Embryo Culture-Derived Barley Regenerants
In vitro tissue culture could be exploited to study cellular mechanisms that induce sequence variation. Altering the metal ion composition of tissue culture medium affects biochemical pathways involved in tissue culture-induced variation. Copper ions are
Renata Orłowska+2 more
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Towards precision quantification of contamination in metagenomic sequencing experiments
Metagenomic next-generation sequencing (mNGS) experiments involving small amounts of nucleic acid input are highly susceptible to erroneous conclusions resulting from unintentional sequencing of occult contaminants, especially those derived from ...
M. S. Zinter+4 more
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Completely mitochondrial genome of Neolissochilus heterostomus
In this study, we determined the complete mitochondrial genome of Neolissochilus heterostomus. The genome is 16,585 bp in length, including 2 ribosomal RNA genes, 13 proteins-coding genes, 22 transfer RNA genes, and two non-coding control regions ...
Jinghong He+5 more
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High-Throughput DNA Analysis Platform Based on an Optofluidic Ring Resonator Laser
We demonstrate an optofluidic laser using DNA microdroplets, an intercalating dye, and a glass capillary ring resonator. Only the target DNA emits the laser signal, while the non-target DNA, including those with single-base mismatches, exhibits zero ...
Chan Seok Jun, Wonsuk Lee
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Determination of sequence similarity is one of the major steps in computational phylogenetic studies. One of the major tasks of computational biologists is to develop novel mathematical descriptors for similarity analysis.
Jie Zhou, Pianyu Zhong, Tinghui Zhang
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Mesoscopic Model for Free Energy Landscape Analysis of DNA sequences [PDF]
A mesoscopic model which allows us to identify and quantify the strength of binding sites in DNA sequences is proposed. The model is based on the Peyrard-Bishop-Dauxois model for the DNA chain coupled to a Brownian particle which explores the sequence interacting more importantly with open base pairs of the DNA chain.
arxiv +1 more source
Bending short DNAs as transversely isotropic rings in series [PDF]
Despite the significance of the high flexibility exhibited by short DNAs, there remains an incomplete understanding of their anomalous persistence length. In this study, we propose a novel approach wherein each fundamental characteristic of gene sequences within short DNAs is modeled as a transversely isotropic ring.
arxiv +1 more source
An auditory display tool for DNA sequence analysis
Background DNA Sonification refers to the use of an auditory display to convey the information content of DNA sequence data. Six sonification algorithms are presented that each produce an auditory display. These algorithms are logically designed from the
Mark D. Temple
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Detection and characterization of tomato leaf curl New Delhi virus association with mosaic disease of ivy gourd (Coccinia grandis (L.) Voigt) in North India [PDF]
Sixteen ivy gourd (Coccinia grandis (L.) Voigt) plant samples showing severe mosaic symptoms were collected from New Delhi and Varanasi (Uttar Pradesh) in India. Begomovirus infection was confirmed by PCR using begomovirusspecific primers.
Venkataravanappa Venkataravanappa+4 more
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