Results 11 to 20 of about 2,821,158 (289)
, 1994 Because a natural entity “species” cannot be recognized as a group of strains that is genetically well separated from its phylogenetic neighbors, a pragmatic approach was taken to define a species by a polyphasic approach (L. G. Wayne, D. J.
E. Stackebrandt, B. Goebel
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Sequencing and Analysis of Neanderthal Genomic DNA [PDF]
Science, 2006 Our knowledge of Neanderthals is based on a limited number of remains and artifacts from which we must make inferences about their biology, behavior, and relationship to ourselves. Here, we describe the characterization of these extinct hominids from a new perspective, based on the development of a Neanderthal metagenomic library and its ...
Jonathan K. Pritchard +12 more
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A Deep Learning Model for Predicting DNA N6-Methyladenine (6mA) Sites in Eukaryotes
IEEE Access, 2020 DNA N6-methyladenine (6mA) is an epigenetic modification, which is involved in many biological regulation processes like DNA replication, DNA repair, transcription, and gene expression regulation.
Lokuthota Hewage Roland +1 more
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DNA sequence analysis of SLC26A5, encoding prestin, in a patient-control cohort: identification of fourteen novel DNA sequence variations. [PDF]
PLoS ONE, 2009 Prestin, encoded by the gene SLC26A5, is a transmembrane protein of the cochlear outer hair cell (OHC). Prestin is required for the somatic electromotile activity of OHCs, which is absent in OHCs and causes severe hearing impairment in mice lacking ...
Jacob S Minor +3 more
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Copper Ions Induce DNA Sequence Variation in Zygotic Embryo Culture-Derived Barley Regenerants
Frontiers in Plant Science, 2021 In vitro tissue culture could be exploited to study cellular mechanisms that induce sequence variation. Altering the metal ion composition of tissue culture medium affects biochemical pathways involved in tissue culture-induced variation. Copper ions are
Renata Orłowska +2 more
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Genetics, 1992 We previously developed a cladistic approach to identify subsets of haplotypes defined by restriction endonuclease mapping or DNA sequencing that are associated with significant phenotypic deviations.
Alan R. Templeton, K. Crandall, C. Sing
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Towards precision quantification of contamination in metagenomic sequencing experiments
Microbiome, 2019 Metagenomic next-generation sequencing (mNGS) experiments involving small amounts of nucleic acid input are highly susceptible to erroneous conclusions resulting from unintentional sequencing of occult contaminants, especially those derived from ...
M. S. Zinter +4 more
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Completely mitochondrial genome of Neolissochilus heterostomus
Mitochondrial DNA. Part B. Resources, 2021 In this study, we determined the complete mitochondrial genome of Neolissochilus heterostomus. The genome is 16,585 bp in length, including 2 ribosomal RNA genes, 13 proteins-coding genes, 22 transfer RNA genes, and two non-coding control regions ...
Jinghong He +5 more
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DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.
Proceedings of the National Academy of Sciences of the United States of America, 1987 A chemically modified phage T7 DNA polymerase has three properties that make it ideal for DNA sequencing by the chain-termination method. The enzyme is highly processive, catalyzing the polymerization of thousands of nucleotides without dissociating.
S. Tabor, C. Richardson
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High-Throughput DNA Analysis Platform Based on an Optofluidic Ring Resonator Laser
Applied Sciences, 2022 We demonstrate an optofluidic laser using DNA microdroplets, an intercalating dye, and a glass capillary ring resonator. Only the target DNA emits the laser signal, while the non-target DNA, including those with single-base mismatches, exhibits zero ...
Chan Seok Jun, Wonsuk Lee
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