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DNA sequence analysis and the computer
Biochemical Society Transactions, 1984Analysis of DNA sequences has greatly aided our understanding of molecular biology and genetics. Nucleotide sequences have provided a wealth of information about gene structure and function. In addition to revealing the primary structure of genes, sequencing has uncovered the phenomena of overlapping genes, segmented genes, pseudogenes and a different ...
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Bioinformatic analysis of DNA sequences
Selection of models of DNA evolution with jModelTest, 2009The storage, processing, description, transmission, connection, and analysis of the waves of new genomic data have made bioinformatics skills essential for scientists working with DNA sequences. In Bioinformatics for DNA Sequence Analysis, experts in the field provide practical guidance and troubleshooting advice for the computational analysis of DNA ...
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Multiresolution Analysis of DNA Sequences
2010 Second International Conference on Computer Research and Development, 2010A wavelet based method for transforming DNA sequences is illustrated by using the small subunit of the ribosome. This paper discusses the application of multi resolution analysis on FASTA-formatted DNA sequences using biorthogonal wavelets. Once transformed, the data could be used for pairwise or multiple sequence alignments needed for studies of ...
Paul Albee +3 more
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Wavelet analysis of DNA sequences
2008 International Conference on Communications, Circuits and Systems, 2008In this paper, the discrete wavelet transform, the complex wavelet transform, and the wavelet packet transform are applied to denoise G and C binary indicator-type of DNA sequences derived from both the Voss representation and the Z curve representation. The technique aims to reveal coding and non-coding regions of genes in a DNA sequence.
R. Atwal +2 more
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Statistical Analysis of DNA Sequences
JNCI Journal of the National Cancer Institute, 1988Developments in the statistical analysis of DNA sequence data since 1984 are reviewed. Mathematical methods employing dynamic programming or incorporating Markov chain theory have been developed to search sequences for regions of similarity and to align sequences.
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Sequence analysis of Leukemia DNA
AIP Conference Proceedings, 2018Cancer is a very deadly disease, one of which is leukemia disease or better known as blood cancer. The cancer cell can be detected by taking DNA in laboratory test. This study focused on local alignment of leukemia and non leukemia data resulting from NCBI in the form of DNA sequences by using Smith-Waterman algorithm.
Muhammad. Isa Irawan +2 more
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statistical analysis of dna sequences [PDF]
, 2007 Wereport recent results of statistical analysis of DNA sequencesin this paper. First, we show howrepetitive segments reduce the information content measured by Shannon entropies. Then, the effect of a nonuniform codon usage on the mutual information function is studied analytically. For this purpose, the concept of pseudo-exons is introduced.
Herzel, Hanspeter +3 more
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Nucleotide sequence analysis of DNA
Journal of Molecular Biology, 1970Abstract A general procedure has been developed for determining the deoxynucleotide sequence of the terminal region of a DNA molecule. When this terminal region is present as a single strand, as in bacteriophage lambda, Escherichia coli DNA polymerase can be used to repair the single-stranded region with the addition of radioactive nucleotides to ...
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Quantitative analysis of DNA-sequencing electrophoresis
Genetic Analysis: Biomolecular Engineering, 1992At the heart of the DNA-sequencing process is a remarkably selective electrophoretic separation of up to 1000 oligonucleotide fragments, each differing in size by only a single nucleotide unit. A quantitative analysis of this separation is performed in terms of both selectivity and efficiency.
Paul D. Grossman +2 more
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[29] Analysis of repeating DNA sequences by reassociation
1974Repetitive DNA occurs widely, if not universally, among higher organisms. A variety of procedures has been developed or adapted to examine its characteristics and a body of concepts and language has grown up to deal with its complexities. This chapter attempts to summarize this body of knowledge and technique.
Britten, Roy J. +2 more
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