Analysis of DNA sequence variation within marine species using Beta-coalescents [PDF]
, 2011 We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially due to extreme
Birkner, Matthias +2 more
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Sequencing and Analysis of Neanderthal Genomic DNA [PDF]
Science, 2006 Our knowledge of Neanderthals is based on a limited number of remains and artifacts from which we must make inferences about their biology, behavior, and relationship to ourselves. Here, we describe the characterization of these extinct hominids from a new perspective, based on the development of a Neanderthal metagenomic library and its ...
Jonathan K. Pritchard +12 more
openaire +5 more sources
DNA sequence analysis of SLC26A5, encoding prestin, in a patient-control cohort: identification of fourteen novel DNA sequence variations. [PDF]
PLoS ONE, 2009 Prestin, encoded by the gene SLC26A5, is a transmembrane protein of the cochlear outer hair cell (OHC). Prestin is required for the somatic electromotile activity of OHCs, which is absent in OHCs and causes severe hearing impairment in mice lacking ...
Jacob S Minor +3 more
doaj +1 more source
Copper Ions Induce DNA Sequence Variation in Zygotic Embryo Culture-Derived Barley Regenerants
Frontiers in Plant Science, 2021 In vitro tissue culture could be exploited to study cellular mechanisms that induce sequence variation. Altering the metal ion composition of tissue culture medium affects biochemical pathways involved in tissue culture-induced variation. Copper ions are
Renata Orłowska +2 more
doaj +1 more source
Towards precision quantification of contamination in metagenomic sequencing experiments
Microbiome, 2019 Metagenomic next-generation sequencing (mNGS) experiments involving small amounts of nucleic acid input are highly susceptible to erroneous conclusions resulting from unintentional sequencing of occult contaminants, especially those derived from ...
M. S. Zinter +4 more
doaj +1 more source
Completely mitochondrial genome of Neolissochilus heterostomus
Mitochondrial DNA. Part B. Resources, 2021 In this study, we determined the complete mitochondrial genome of Neolissochilus heterostomus. The genome is 16,585 bp in length, including 2 ribosomal RNA genes, 13 proteins-coding genes, 22 transfer RNA genes, and two non-coding control regions ...
Jinghong He +5 more
doaj +1 more source
From Nonspecific DNA–Protein Encounter Complexes to the Prediction of DNA–Protein Interactions [PDF]
, 2009 ©2009 Gao, Skolnick. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Sarai +49 more
core +4 more sources
A Deep Learning Model for Predicting DNA N6-Methyladenine (6mA) Sites in Eukaryotes
IEEE Access, 2020 DNA N6-methyladenine (6mA) is an epigenetic modification, which is involved in many biological regulation processes like DNA replication, DNA repair, transcription, and gene expression regulation.
Lokuthota Hewage Roland +1 more
doaj +1 more source
High-Throughput DNA Analysis Platform Based on an Optofluidic Ring Resonator Laser
Applied Sciences, 2022 We demonstrate an optofluidic laser using DNA microdroplets, an intercalating dye, and a glass capillary ring resonator. Only the target DNA emits the laser signal, while the non-target DNA, including those with single-base mismatches, exhibits zero ...
Chan Seok Jun, Wonsuk Lee
doaj +1 more source
Cloning and characterisation of the S.pombe rad15 gene, a homologue to the S.cerevisiae RAD3 and human ERCC2 genes [PDF]
, 1992 The RAD3 gene of Saccharomyces cerevisiae encodes an ATP-dependent 5' - 3' DNA helicase, which is involved in excision repair of ultraviolet radiation damage.
Alan R. Lehmann +6 more
core +3 more sources