Results 51 to 60 of about 1,609,143 (313)

Genome analysis of a Glossina pallidipes salivary gland hypertrophy virus reveals a novel, large, double-stranded circular DNA virus

, 2008
Several species of tsetse flies can be infected by the Glossina pallidipes salivary gland hypertrophy virus (GpSGHV). Infection causes salivary gland hypertrophy and also significantly reduces the fecundity of the infected flies. To better understand the
Parker, Andrew G., Robinson, Alan S., Abd-Alla, A.M.M., Cousserans, F., Vlak, J.M., Cousserans, Francois, F., Jehle, Johannes A., Bergoin, Max, Parker, A.G., Bergoin, M., Abd-Alla, Adly M. M., Vlak, Just M., Jehle, J.A., Parker, N.J., Robinson, A.S., Parker, Nicolas J.   +15 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Seven-Cluster Structure of Larch Chloroplast Genome [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2015
The paper presents a novel approach to study a nucleotide sequence structure with respect to the chloroplast genome DNA sequence analysis. A specific frequencies distribution pattern of the consecutive triple nucleotide fragments was identified in the ...
Michael G. Sadovsky, Eugenia I. Bondar, Yulia A. Putintseva, Natalia V. Oreshkova, Eugene A. Vaganov, Konstantin V. Krutovsky   +5 more
doaj   +1 more source

A sequence-based 163plex microhaplotype assay for forensic DNA analysis

Frontiers in Genetics, 2022
Novel genetic marker microhaplotype has led to an upsurge in forensic genetic research. This study established a 163 microhaplotype (MH) multiplex assay based on next-generation sequencing (NGS) and evaluated the assay’s performance and applicability ...
Ruiyang Tao, Qi Yang, Ruocheng Xia, Xiaochun Zhang, Anqi Chen, Chengtao Li, Suhua Zhang   +6 more
doaj   +1 more source

Analysis of the giant genomes of Fritillaria (Liliaceae) indicates that a lack of DNA removal characterizes extreme expansions in genome size. [PDF]

, 2015
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.Plants exhibit an extraordinary range of genome sizes,
Novák, P, Pellicer, J., Fay, M. F., Leitch, IJ, Neumann, P., Peter D. Day, Leitch, A. R., Pellicer, J, Michael F. Fay, Petr Novák, Ilia J. Leitch, Day, PD, Kelly, L. J., Richard A. Nichols, Pavel Neumann, Lysak, M. A., Laura J. Kelly, Neumann, P, Jaume Pellicer, Nichols, RA, Andrew R. Leitch, Macas, J., Macas, J, Novak, P., Leitch, I. J., Lysak, M., Berger, M., Lysak, MA, Day, P. D., Martin A. Lysak, Renny-Byfield, S, Leitch, AR, Nichols, R. A., Jiří Macas, Simon Renny‐Byfield, Kelly, LJ, Berger, M, Fay, MF, Madeleine Berger, Renny-Byfield, S.   +39 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Understanding the sequence-dependence of DNA groove dimensions: implications for DNA interactions. [PDF]

PLoS ONE, 2010
BACKGROUND: The B-DNA major and minor groove dimensions are crucial for DNA-protein interactions. It has long been thought that the groove dimensions depend on the DNA sequence, however this relationship has remained elusive.
Christophe Oguey, Nicolas Foloppe, Brigitte Hartmann   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A conserved sequence extending motif III of the motor domain in the Snf2-family DNA translocase Rad54 is critical for ATPase activity. [PDF]

PLoS ONE, 2013
Rad54 is a dsDNA-dependent ATPase that translocates on duplex DNA. Its ATPase function is essential for homologous recombination, a pathway critical for meiotic chromosome segregation, repair of complex DNA damage, and recovery of stalled or broken ...
Xiao-Ping Zhang, Ryan Janke, James Kingsley, Jerry Luo, Clare Fasching, Kirk T Ehmsen, Wolf-Dietrich Heyer   +6 more
doaj   +1 more source

Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by gram-negative and gram-positive type II DNA topoisomerases [PDF]

, 2007
Bacterial DNA gyrase and topoisomerase IV are selective targets of fluoroquinolones. Topoisomerase IV versus gyrase and Gram-positive versus Gram-negative behavior was studied based on the different recognition of DNA sequences by topoisomerase ...
GIARETTA G, COMUZZI V, Palumbo, M, Leo, E, Mitchenall, LA, Richter, SN, Maxwell, A, Fisher, LM, RICHTER, SARA, Giaretta, G, LEO E, MAXWELL A, Comuzzi, V, FISHER LM, MITCHENALL LA, PALUMBO, MANLIO   +15 more
core   +1 more source