Results 71 to 80 of about 2,798,032 (288)
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Molecular characterization of events is an integral part of the advancement process during genetically modified (GM) crop product development. Assessment of these events is traditionally accomplished by polymerase chain reaction (PCR) and Southern blot ...
Gina M. Zastrow-Hayes+9 more
doaj +1 more source
Molecular characterization of Colletotrichum species causing Begonia anthracnose in Sri Lanka
Anthracnose disease is known to affect many tropical and subtropical fruits, vegetables and also certain cut-flowers and foliage plants. The disease was known to be caused by Colletotrichum gloeosporioides or C.
P. Wickramasinghe+2 more
doaj +1 more source
Application of neural networks and other machine learning algorithms to DNA sequence analysis
In this article we report initial, quantitative results on application of simple neutral networks, and simple machine learning methods, to two problems in DNA sequence analysis.
A. Lapedes+4 more
semanticscholar +1 more source
Sequence analysis by additive scales: DNA structure for sequences and repeats of all lengths
MOTIVATION DNA structure plays an important role in a variety of biological processes. Different di- and tri-nucleotide scales have been proposed to capture various aspects of DNA structure including base stacking energy, propeller twist angle, protein ...
P. Baldi, Pierre-François Baisnée
semanticscholar +1 more source
A computer package for DNA sequence analysis
We have developed a comprehensive software-hardware package for a CP/M based or other microcomputer which can perform four major functions in a molecular biology laboratory: (1) the acquisition and analysis of DNA sequence data, (2) word processing in the preparation of scientific manuscripts and figures, (3) general lab computation and data reduction,
John L. Schroeder, Frederick R. Blattner
openaire +4 more sources
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations [PDF]
Background. Massively parallel sequencing technology is being used to sequence highly diverse populations of DNA such as that derived from heterogeneous cell mixtures containing both wild-type and disease-related states.
T. Daniel Andrews+4 more
doaj +2 more sources
The inter- and intrageneric relationships of members of the genus Acinetobacter were investigated by performing a comparative sequence analysis of PCR-amplified 16S ribosomal DNAs (rDNAs) from 21 strains representing all of the DNA groups that have been ...
Ashraf Ibrahim+2 more
semanticscholar +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source