Results 81 to 90 of about 26,765,029 (301)

Structure of 5S rDNA sequence of the gibel carp (Carassius gibelio) with 2n=100 chromosomes

open access: yesFrontiers in Marine Science, 2015
In vertebrate, the 5S ribosomal DNA (rDNA) consists of a conserved coding (transcriptional) unit of 120 bp (5S), which is separated from the next unit by a nontranscribed spacer (NTS). The coding sequence and the NTS together form a repeat unit which can
Lech Kirtiklis
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by gram-negative and gram-positive type II DNA topoisomerases [PDF]

open access: yes, 2007
Bacterial DNA gyrase and topoisomerase IV are selective targets of fluoroquinolones. Topoisomerase IV versus gyrase and Gram-positive versus Gram-negative behavior was studied based on the different recognition of DNA sequences by topoisomerase ...
GIARETTA G   +15 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Segmenting DNA sequence into words based on statistical language model [PDF]

open access: yes, 2012
This paper presents a novel method to segment/decode DNA sequences based on n-gram statistical language model. Firstly, we find the length of most DNA “words” is 12 to 15 bps by analyzing the genomes of 12 model species.
Wang Liang
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Advances in DNA sequence specific agents : a research annual.

open access: yes, 1998
In this volume the entire focus is devoted to the macromolecule target specificity of DNA interactive developmental therapeutic agents of current interest.
Hurley, Laurence H.,éd.
core  

Molecular characterization and subtyping of Blastocystis in urticarial patients in Turkey

open access: yesAsian Pacific Journal of Tropical Medicine, 2019
Objective: To investigate Blastocystis’ etiologic role and association with gastrointestinal symptomatology in acute and chronic urticaria patients and to identify Blastocystis subtypes responsible for urticaria.
Merve Aydin   +8 more
doaj   +1 more source

Characterization of the complete mitochondrial genome of Euspira gilva with phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2020
Here, we determined the complete mitogenome sequence of Euspira gilva (Littorinimorpha: Naticidae). The complete mitochondrial genome is circular and 16,119 bp in length, containing 13 protein-coding genes (PCGs), 2 ribosomal RNA genes, and 22 transfer ...
Zongxing Wang   +5 more
doaj   +1 more source

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