Results 231 to 240 of about 2,818,524 (302)

Enzyme Engineering Database (EnzEngDB): a platform for sharing and interpreting sequence-function relationships across protein engineering campaigns. [PDF]

Nucleic Acids Res
Long Y, Abbasinejad F, Li FZ, Reinprecht P, Wittmann B, Kennemur JL, Carder H, Yang J, Lambert T, O'Meara R, Radtke L, Qin Z, Brinkmann-Chen S, Arnold F, Mora A.   +14 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

GeneFamily: a comprehensive mammalian gene family database with extensive annotation and interactive visualization. [PDF]

Nucleic Acids Res
Wang Y, Zhang Y, Wang X, Ng YK, Jia Y, Zhao Z, Liu J, Yang S, Shen B, Li SC.   +9 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Novel snake <i>Circovirus</i> from alpine pit viper (<i>Gloydius strauchi</i>) in China: evidence of a mammal-avian genetic recombinant. [PDF]

Front Microbiol
Tian Z, Luo S, Li J, Liu X, Huang Y, Fan Y, Zhou C, Guo P, Hu X.   +8 more
europepmc   +1 more source

The Characteristics and Expression of <i>RBX1</i> Gene Involved in Ovarian Development of <i>Scylla paramamosain</i>. [PDF]

Int J Mol Sci
Zhang F, Huang T, Ren Y, Zhao M, Wang W, Liu Z, Ma K, Fu Y, Chen W, Ma L, Ma C.   +10 more
europepmc   +1 more source

Molecular-level protein semantic learning via structure-aware coarse-grained language modeling. [PDF]

Bioinformatics
Zhang J, Weng X, Zhu T, Liu Y, Zhu Z.
europepmc   +1 more source

Verification and comparison of pig, mouse, and human genome similarities: use of manual assembly and analyses. [PDF]

BMC Genomics
Dawson HD, Chen CT, Ragonese JS, Smith AD, Lunney JK.   +4 more
europepmc   +1 more source

A metagenomic analysis of urban river samples reveals high numbers of sequences related to mycoviruses. [PDF]

Arch Virol
Zell R, Groth M, Selinka L, Selinka HC.
europepmc   +1 more source