Results 21 to 30 of about 2,818,524 (302)

iSeqSearch: incremental protein search for iBlast/iMMSeqs2/iDiamond [PDF]

PeerJ
Background The advancement of sequencing technology has led to a rapid increase in the amount of DNA and protein sequence data; consequently, the size of genomic and proteomic databases is constantly growing.
Hyunwoo Yoo, Mohammadsaleh Refahi, Robi Polikar, Bahrad A. Sokhansanj, James R. Brown, Gail L. Rosen   +5 more
doaj   +2 more sources

Real or fake? Measuring the impact of protein annotation errors on estimates of domain gain and loss events

Frontiers in Bioinformatics, 2023
Protein annotation errors can have significant consequences in a wide range of fields, ranging from protein structure and function prediction to biomedical research, drug discovery, and biotechnology.
Arnaud Kress, Olivier Poch, Odile Lecompte, Julie D. Thompson   +3 more
doaj   +1 more source

Species-specific analysis of protein sequence motifs using mutual information

BMC Bioinformatics, 2005
Background Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles derived from multiple sequence alignments provide an alternative description ...
Weckwerth Wolfram, Keshvari Nima, Hummel Jan, Selbig Joachim   +3 more
doaj   +1 more source

Sequence of a putative human housekeeping gene (HK33) localized on chromosome 1 [PDF]

, 1994
A gene (X33) localized on human chromosome 1 has been detected by crossreaction of its fusion protein with a monospecific antiserum directed against human vitamin-D-binding protein (hDBP; group-specific component).
Chirgwin, Church, Estaller, Feinberg, Hoffmann, Johnson, Kozak, Manley, McLeod, Meissner, Proudfood, Proudfood, Prunier, Sambrook, Sanger, Sheets, Smith, Tabor, Yanisch-Perron   +18 more
core   +1 more source

BMC Caller: a webtool to identify and analyze bacterial microcompartment types in sequence data

Biology Direct, 2022
Bacterial microcompartments (BMCs) are protein-based organelles found across the bacterial tree of life. They consist of a shell, made of proteins that oligomerize into hexagonally and pentagonally shaped building blocks, that surrounds enzymes ...
Markus Sutter, Cheryl A. Kerfeld
doaj   +1 more source

Herding cats: Label-based approaches in protein translocation through nanopore sensors for single-molecule protein sequence analysis

iScience, 2021
Summary: Proteins carry out life's essential functions. Comprehensive proteome analysis technologies are thus required for a full understanding of the operating principles of biological systems. While current proteomics techniques suffer from limitations
Keisuke Motone, Nicolas Cardozo, Jeff Nivala   +2 more
doaj   +1 more source

CAPS: coevolution analysis using protein sequences [PDF]

Bioinformatics, 2006
Abstract Summary: Coevolution Analysis using Protein Sequences (CAPS) is a PERL based software that identifies co-evolution between amino acid sites. Blosum-corrected amino acid distances are used to identify amino acid co-variation. The phylogenetic sequence relationships are used to remove the phylogenetic and stochastic dependencies ...
Mario A, Fares, David, McNally
openaire   +2 more sources

Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin [PDF]

, 1997
The cornified envelope is a layer of transglutaminase cross-linked protein that is assembled under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Argos, Arnemann, Bernier, Chou, Claros, Duden, Fey, Foisner, Foisner, Garnier, Green, Green, Guo, Haftek, Heid, Huber, Ishida-Yamamoto, Knight, Kouklis, Kozak, Kyte, Lupas, Ma, Maestrini, McLachlan, McLean, Ming, Nicholson, Nikolic, Ouyang, Parrish, Parry, Pasdar, Pasdar, Rice, Robinson, Ruhrberg, Ruhrberg, Sawamura, Sawamura, Schmidt, Sheu, Siefring, Simon, Stappenbeck, Stappenbeck, Stappenbeck, Steinert, Steinert, Sun, Surya, Svitkina, Tang, Uitto, Virata, Wiche, Wiche, Yang   +57 more
core   +2 more sources

Filtering Degenerate Patterns with Application to Protein Sequence Analysis

Algorithms, 2013
In biology, the notion of degenerate pattern plays a central role for describing various phenomena. For example, protein active site patterns, like those contained in the PROSITE database, e.g., [FY ]DPC[LIM][ASG]C[ASG], are, in general, represented by ...
Matteo Comin, Davide Verzotto
doaj   +1 more source

Computational curation and analysis of publicly available protein sequence data from a single protein family

MethodsX, 2022
The wealth of sequence data available on public databases is increasing at an exponential rate, and while tremendous efforts are being made to make access to these resources easier, these data can be challenging for researchers to reuse because ...
Kyra Dougherty, Katalin A. Hudak
doaj   +1 more source