Results 31 to 40 of about 5,258,715 (348)

Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions.

open access: yesDNA Research, 1996
The sequence determination of the entire genome of the Synechocystis sp. strain PCC6803 was completed. The total length of the genome finally confirmed was 3,573,470 bp, including the previously reported sequence of 1,003,450 bp from map position 64% to ...
Takakazu   +45 more
semanticscholar   +1 more source

Cloning and characterisation of the rad9 DNA repair gene from Schizosaccharomyces pombe [PDF]

open access: yes, 1991
The rad9.192 DNA repair mutant from the fission yeast, Schizosaccharomyces pombe, is sensitive to both UV and ionising radiation. The rad9 gene has been cloned by complementation of the gamma-ray sensitivity of the mutant cell line.
Carr, Antony M   +3 more
core   +2 more sources

iSeqSearch: incremental protein search for iBlast/iMMSeqs2/iDiamond [PDF]

open access: yesPeerJ
Background The advancement of sequencing technology has led to a rapid increase in the amount of DNA and protein sequence data; consequently, the size of genomic and proteomic databases is constantly growing.
Hyunwoo Yoo   +5 more
doaj   +2 more sources

Real or fake? Measuring the impact of protein annotation errors on estimates of domain gain and loss events

open access: yesFrontiers in Bioinformatics, 2023
Protein annotation errors can have significant consequences in a wide range of fields, ranging from protein structure and function prediction to biomedical research, drug discovery, and biotechnology.
Arnaud Kress   +3 more
doaj   +1 more source

Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis. [PDF]

open access: yes, 2016
Identification and annotation of functional residues are fundamental questions in protein sequence analysis. Sequence and structure conservation provides valuable information to tackle these questions.
Du, Yushen   +7 more
core   +2 more sources

ConSole: using modularity of contact maps to locate solenoid domains in protein structures. [PDF]

open access: yes, 2014
BackgroundPeriodic proteins, characterized by the presence of multiple repeats of short motifs, form an interesting and seldom-studied group. Due to often extreme divergence in sequence, detection and analysis of such motifs is performed more reliably on
Godzik, Adam, Hrabe, Thomas
core   +4 more sources

BMC Caller: a webtool to identify and analyze bacterial microcompartment types in sequence data

open access: yesBiology Direct, 2022
Bacterial microcompartments (BMCs) are protein-based organelles found across the bacterial tree of life. They consist of a shell, made of proteins that oligomerize into hexagonally and pentagonally shaped building blocks, that surrounds enzymes ...
Markus Sutter, Cheryl A. Kerfeld
doaj   +1 more source

Analysis of protein-coding genetic variation in 60,706 humans

open access: yesNature, 2015
Large-scale reference data sets of human genetic variation are critical for the medical and functional interpretation of DNA sequence changes. Here we describe the aggregation and analysis of high-quality exome (protein-coding region) DNA sequence data ...
James Y. Zou
semanticscholar   +1 more source

Sequence analysis of the AAA protein family [PDF]

open access: yesProtein Science, 1997
AbstractThe AAA protein family, a recently recognized group of Walker‐type ATPases, has been subjected to an extensive sequence analysis. Multiple sequence alignments revealed the existence of a region of sequence similarity, the so‐called AAA cassette.
A. Beyer
semanticscholar   +4 more sources

Problems Affecting Labor [PDF]

open access: yes, 1944
Much experimental work has been devoted in comparing the folding behavior of proteins sharing the same fold but different sequence. The recent design of proteins displaying very high sequence identities but different 3D structure allows the unique ...
Brunori, M.   +5 more
core   +5 more sources

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