Results 81 to 90 of about 2,818,524 (302)
Bioinformatic analysis of THAP9 transposase homolog: conserved regions, novel motifs
Current Research in Structural BiologyTHAP9 is a transposable element-derived gene that encodes the THAP9 protein, which is homologous to the Drosophila P-element transposase (DmTNP) and can cut and paste DNA. However, the exact functional role of THAP9 is unknown. Here, we perform structure
Richa Rashmi +2 more
doaj +1 more source
Word correlation matrices for protein sequence analysis and remote homology detection
BMC Bioinformatics, 2008 Background Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provide the most accurate results.
Meinicke Peter, Lingner Thomas
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High-sensitive protein sequence analysis [PDF]
Pure and Applied Chemistry, 1992 Abstract
openaire +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
In silico study of Bacillus spB201 amylase through protein sequence inspection
Journal of the Arab Society for Medical ResearchBackground/aim Bioinformatics is the automatic processing of biological information, and it is a helpful tool to study the structure-function relationship of various proteins.
Sameh Ben Mabrouk +3 more
doaj +1 more source
REPARATION : ribosome profiling assisted (re-)annotation of bacterial genomes [PDF]
, 2017 Prokaryotic genome annotation is highly dependent on automated methods, as manual curation cannot keep up with the exponential growth of sequenced genomes.
Giess, Adam +5 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The Computer‐Assisted Sequence Annotation (CASA) workflow for enzyme discovery
Applications in Plant SciencesPremise With the advent of inexpensive nucleic acid sequencing and automated annotation at the level of basic functionality, the central problem of enzyme discovery is no longer finding active sequences, it is determining which ones are suitable for ...
Gemma R. Takahashi +3 more
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Amino acid sequence of rabbit apolipoprotein E.
Journal of Lipid Research, 1991 The complete amino acid sequence of rabbit apolipoprotein E (apoE) was determined by generating three sets of peptides using cyanogen bromide, endoproteinase AspN, and Staphylococcus aureus V8 protease to cleave the protein.
BR Lee +6 more
doaj +1 more source
Rapid pre-gel visualization of proteins with mass spectrometry compatibility [PDF]
, 2010 Despite all of the prophecies of doom, gel electrophoresis is still prevalent in modern proteomic workflows. However, the currently used protein staining methods represent a serious bottleneck for a quick subsequent protein analysis using mass ...
Marco A. Mata-Gomez +2 more
core +1 more source