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Current Developments in RNA Sequence Analysis

Bioinformatics and Biology Insights, 2015
field with online, open access to highly relevant scholarly articles by leading international researchers. In a field where the literature is ever-expanding, researchers increasingly need access to up-to-date, high quality scholarly articles on areas of specific contemporary interest.
Jianping Zhang, Shaolei Teng, Cuncong Zhong, Bo Wang, Jie Wu   +4 more
doaj   +4 more sources

Recent advances in RNA sequence analysis [PDF]

F1000 Biology Reports, 2010
The latest high-throughput DNA sequencing technology can now be applied on a large scale to capture the complete set of mRNA transcripts in a cell, using a technique called RNA-seq.
Salzberg, Steven L
core   +6 more sources

Sequence variant analysis of RNA sequences in severe equine asthma [PDF]

PeerJ, 2018
Background Severe equine asthma is a chronic inflammatory disease of the lung in horses similar to low-Th2 late-onset asthma in humans. This study aimed to determine the utility of RNA-Seq to call gene sequence variants, and to identify sequence variants
Laurence Tessier, Olivier Côté, Dorothee Bienzle   +2 more
doaj   +4 more sources

Noncoding RNA gene detection using comparative sequence analysis [PDF]

BMC Bioinformatics, 2001
Background Noncoding RNA genes produce transcripts that exert their function without ever producing proteins. Noncoding RNA gene sequences do not have strong statistical signals, unlike protein coding genes.
Eddy Sean R, Rivas Elena
doaj   +5 more sources

A complex adaptive systems approach to the kinetic folding of RNA [PDF]

, 2005
The kinetic folding of RNA sequences into secondary structures is modeled as a complex adaptive system, the components of which are possible RNA structural rearrangements (SRs) and their associated bases and base pairs. RNA bases and base pairs engage in local stacking interactions that determine the probabilities (or fitnesses) of possible SRs ...
Abrahams, Baker, Cannone, Fisher, Flamm, Fontana, Freier, Gratias, Gultyaev, Hadany, Higgs, Hofacker, Isambert, Kauffman, Kauffman, Kawasaki, Lee, Levin, Mathews, Mathews, McCarthy, Metropolis, Mironov, Mochizuki, Morgan, Nagel, Ndifon, Poerschke, Poerschke, Schuster, Schuster, Schuster, Skellett, Tang, Vitreschack, Wilfred Ndifon, Woese, Wolfinger, Xayaphoummine, Yang, Zamora, Zhang   +41 more
arxiv   +5 more sources

ScanFold 2.0: a rapid approach for identifying potential structured RNA targets in genomes and transcriptomes [PDF]

PeerJ, 2022
A major limiting factor in target discovery for both basic research and therapeutic intervention is the identification of structural and/or functional RNA elements in genomes and transcriptomes.
Ryan J. Andrews, Warren B. Rouse, Collin A. O’Leary, Nicholas J. Booher, Walter N. Moss   +4 more
doaj   +2 more sources

Small RNA sequencing profiles of mir-181 and mir-221, the most relevant microRNAs in acute myeloid leukemia [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims To evaluate and select microRNAs relevant to acute myeloid leukemia (AML) pathogenesis, we analyzed differential microRNA expression by quantitative small RNA next-generation sequencing using duplicate marrow samples from individual AML ...
Yun-Gyoo Lee, Inho Kim, Somi Oh, Dong-Yeop Shin, Youngil Koh, Keun-Wook Lee   +5 more
doaj   +1 more source

RNA Sequencing and Analysis [PDF]

Cold Spring Harbor Protocols, 2015
RNA sequencing (RNA-Seq) uses the capabilities of high-throughput sequencing methods to provide insight into the transcriptome of a cell. Compared to previous Sanger sequencing- and microarray-based methods, RNA-Seq provides far higher coverage and greater resolution of the dynamic nature of the transcriptome.
Kimberly R. Kukurba, Stephen B. Montgomery   +1 more
openaire   +3 more sources

Computational Analysis of RNA Nucleotide Sequences [PDF]

International Journal of Trend in Scientific Research and Development, 2019
One of the most fascinating and deeply researched fields of all of the biochemical components are the nucleic acids and proteins, especially because of their dynamic structure and function and their fundamental role in the course of evolution. Sequence studies have been carried out and is still being researched on to decode completely the world of ...
Shall Juneja, Deepayan Mukherjee, Sachi Garg   +2 more
openaire   +1 more source

Development of strategies for SNP detection in RNA-seq data: application to lymphoblastoid cell lines and evaluation using 1000 Genomes data. [PDF]

PLoS ONE, 2013
Next-generation RNA sequencing (RNA-seq) maps and analyzes transcriptomes and generates data on sequence variation in expressed genes. There are few reported studies on analysis strategies to maximize the yield of quality RNA-seq SNP data.
Emma M Quinn, Paul Cormican, Elaine M Kenny, Matthew Hill, Richard Anney, Michael Gill, Aiden P Corvin, Derek W Morris   +7 more
doaj   +1 more source