Results 31 to 40 of about 1,742,697 (207)

RNA-sequence analysis of human B-cells [PDF]

open access: yesGenome Research, 2011
RNA-sequencing (RNA-seq) allows quantitative measurement of expression levels of genes and their transcripts. In this study, we sequenced complementary DNA fragments of cultured human B-cells and obtained 879 million 50-bp reads comprising 44 Gb of sequence.
Jonathan M, Toung   +3 more
openaire   +2 more sources

Streamlining Quantitative Analysis of Long RNA Sequencing Reads [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Transcriptome analyses allow for linking RNA expression profiles to cellular pathways and phenotypes. Despite improvements in sequencing methodology, whole transcriptome analyses are still tedious, especially for methodologies producing long reads. Currently, available data analysis software often lacks cost- and time-efficient workflows.
Sebastian Oeck   +3 more
openaire   +5 more sources

Expanding the repertoire of human tandem repeat RNA-binding proteins.

open access: yesPLoS ONE, 2023
Protein regions consisting of arrays of tandem repeats are known to bind other molecular partners, including nucleic acid molecules. Although the interactions between repeat proteins and DNA are already widely explored, studies characterising tandem ...
Agustín Ormazábal   +6 more
doaj   +1 more source

Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors. [PDF]

open access: yes, 2017
Aptamers consist of short oligonucleotides that bind specific targets. They provide advantages over antibodies, including robustness, low cost, and reusability.
Jeddi, Iman, Saiz, Leonor
core   +2 more sources

Tracking Cryptosporidium parvum by Sequence Analysis of Small Double-Stranded RNA

open access: yesEmerging Infectious Diseases, 2001
We sequenced a 173-nucleotide fragment of the small double-stranded viruslike RNA of Cryptosporidium parvum isolates from 23 calves and 38 humans. Sequence diversity was detected at 17 sites.
Lihua Xiao   +3 more
doaj   +1 more source

Ribovore: ribosomal RNA sequence analysis for GenBank submissions and database curation

open access: yesBMC Bioinformatics, 2021
Background The DNA sequences encoding ribosomal RNA genes (rRNAs) are commonly used as markers to identify species, including in metagenomics samples that may combine many organismal communities.
Alejandro A. Schäffer   +7 more
doaj   +1 more source

The First Complete Genome Sequence of a Novel Tetrastichus brontispae RNA Virus-1 (TbRV-1)

open access: yesViruses, 2019
The complete sequence of a novel RNA virus isolated from Tetrastichus brontispae (TbRV-1) was determined to be 12,239 nucleotides in length with five non-overlapping, linearly arranged coding sequences (CDS), potentially encoding nucleoproteins ...
E Meng   +8 more
doaj   +1 more source

PRADA: pipeline for RNA sequencing data analysis [PDF]

open access: yesBioinformatics, 2014
Abstract Summary:  Technological advances in high-throughput sequencing necessitate improved computational tools for processing and analyzing large-scale datasets in a systematic automated manner. For that purpose, we have developed PRADA (Pipeline for RNA-Sequencing Data Analysis), a flexible, modular and highly scalable software ...
Wandaliz, Torres-García   +9 more
openaire   +2 more sources

Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements. [PDF]

open access: yes, 2017
In single stranded (+)-sense RNA viruses, RNA structural elements (SEs) play essential roles in the infection process from replication to encapsidation.
Aviran, Sharon   +5 more
core   +2 more sources

Intelligent deep analysis of DNA sequences based on FFGM to enhancement the performance and reduce the computation

open access: yesEgyptian Informatics Journal, 2023
In an attempt to improve the analysis DNA sequence, a new intelligent deep analysis algorithm called reduce frequency bast on fast frequency graph mining (RF-FFGM) is established; This algorithm at the beginning converts the DNA sequence into RNA ...
Zena A. Kadhuim, Samaher Al-Janabi
doaj   +1 more source

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