Results 41 to 50 of about 1,683,944 (287)

Statistical Design and Analysis of RNA Sequencing Data [PDF]

open access: yesGenetics, 2010
AbstractNext-generation sequencing technologies are quickly becoming the preferred approach for characterizing and quantifying entire genomes. Even though data produced from these technologies are proving to be the most informative of any thus far, very little attention has been paid to fundamental design aspects of data collection and analysis, namely
Paul L. Auer, Rebecca W. Doerge
openaire   +3 more sources

A Systematic Bioinformatics Workflow With Meta-Analytics Identified Potential Pathogenic Factors of Alzheimer’s Disease

open access: yesFrontiers in Neuroscience, 2020
Potential pathogenic factors, other than well-known APP, APOE4, and PSEN, can be further identified from transcriptomics studies of differentially expressed genes (DEGs) that are specific for Alzheimer’s disease (AD), but findings are often inconsistent ...
Sze Chung Yuen   +3 more
doaj   +1 more source

Sequence motifs that distinguish ATP(CTP) : tRNA nucleotidyl transferases from eubacterial poly(A) polymerases [PDF]

open access: yes, 2004
ATP(CTP):tRNA nucleotidyl transferases, tRNA maturing enzymes found in all organisms, and eubacterial poly(A) polymerases, enzymes involved in mRNA degradation, are so similar that until now their biochemical functions could not be distinguished by their
Keller, W., Martin, G.
core   +2 more sources

Metagenomic Analysis of Marigold: Mixed Infection Including Two New Viruses

open access: yesViruses, 2021
Marigold plants with symptoms of mosaic, crinkle, leaf curl and necrosis were observed and small RNA and ribo-depleted total RNA deep sequencing were conducted to identify the associated viruses.
Hang Yin   +7 more
doaj   +1 more source

RNA sequencing analysis of the developing chicken retina

open access: yesScientific Data, 2016
AbstractRNA sequencing transcriptome analysis using massively parallel next generation sequencing technology provides the capability to understand global changes in gene expression throughout a range of tissue samples. Development of the vertebrate retina requires complex temporal orchestration of transcriptional activation and repression.
Langouet-Astrie, Christophe J.   +4 more
openaire   +2 more sources

Geometric combinatorics and computational molecular biology: branching polytopes for RNA sequences

open access: yes, 2016
Questions in computational molecular biology generate various discrete optimization problems, such as DNA sequence alignment and RNA secondary structure prediction.
Drellich, Elizabeth   +5 more
core   +1 more source

Structural Alignment of RNAs Using Profile-csHMMs and Its Application to RNA Homology Search: Overview and New Results [PDF]

open access: yes, 2008
Systematic research on noncoding RNAs (ncRNAs) has revealed that many ncRNAs are actively involved in various biological networks. Therefore, in order to fully understand the mechanisms of these networks, it is crucial to understand the roles of ncRNAs ...
Vaidyanathan, P. P., Yoon, Byung-Jun
core   +2 more sources

Encryption of Stereo Image Based on Fractional Chaotic System and RNA Encoding

open access: yesTaiyuan Ligong Daxue xuebao, 2021
For the increasingly wide usage of stereo images, a stereo image encryption algorithm based on fractional-order hyper-chaotic system and dynamic Ribonucleic Acid (RNA) encoding was proposed. In the chaotic sequence generation stage, SHA-256 hash function
Zhenyu LI   +3 more
doaj   +1 more source

A Beginner’s Guide to Analysis of RNA Sequencing Data [PDF]

open access: yesAmerican Journal of Respiratory Cell and Molecular Biology, 2018
Since the first publications coining the term RNA-seq (RNA sequencing) appeared in 2008, the number of publications containing RNA-seq data has grown exponentially, hitting an all-time high of 2,808 publications in 2016 (PubMed). With this wealth of RNA-seq data being generated, it is a challenge to extract maximal meaning from these datasets, and ...
Elizabeth T. Bartom   +6 more
openaire   +3 more sources

Discovery of RNA secondary structural motifs using sequence-ordered thermodynamic stability and comparative sequence analysis

open access: yesMethodsX, 2023
Major advances in RNA secondary structural motif prediction have been achieved in the last few years; however, few methods harness the predictive power of multiple approaches to deliver in-depth characterizations of local RNA motifs and their potential ...
Jake M. Peterson   +4 more
doaj  

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