Results 41 to 50 of about 1,742,697 (207)
Geometric combinatorics and computational molecular biology: branching polytopes for RNA sequences
, 2016 Questions in computational molecular biology generate various discrete optimization problems, such as DNA sequence alignment and RNA secondary structure prediction.
Drellich, Elizabeth +5 more
core +1 more source
HeliyonDeciphering information of RNA sequences reveals their diverse roles in living organisms, including gene regulation and protein synthesis. Aberrations in RNA sequence such as dysregulation and mutations can drive a diverse spectrum of diseases including ...
Muhammad Nabeel Asim +3 more
doaj +1 more source
Dataset of the transcribed 45S ribosomal RNA sequence of the tree crop yerba mate [PDF]
, 2017 This contribution contains data related to the research article entitled The 18S-25S ribosomal RNA unit of yerba mate (Ilex paraguariensis A. St.-Hil.) (Aguilera et al., 2016).
Aguilera, Patricia Mabel +2 more
core +2 more sources
Comparative Analysis of Single-Cell RNA Sequencing Methods [PDF]
Molecular Cell, 2017 Single-cell RNA sequencing (scRNA-seq) offers new possibilities to address biological and medical questions. However, systematic comparisons of the performance of diverse scRNA-seq protocols are lacking. We generated data from 583 mouse embryonic stem cells to evaluate six prominent scRNA-seq methods: CEL-seq2, Drop-seq, MARS-seq, SCRB-seq, Smart-seq ...
Ziegenhain, Christoph +9 more
openaire +3 more sources
陆军军医大学学报Objective To analyze the composition characteristics and biological functions of tumor cell subpopulations in glioblastoma (GBM) through multi-transcriptomics sequencing technology, and explore the hypoxia characteristics and spatial localization ...
CHEN Tao, YANG Fan, WANG Shuai
doaj +1 more source
Global analysis of RNA cleavage by 5′-hydroxyl RNA sequencing [PDF]
Nucleic Acids Research, 2015 RNA cleavage by some endoribonucleases and self-cleaving ribozymes produces RNA fragments with 5'-hydroxyl (5'-OH) and 2',3'-cyclic phosphate termini. To identify 5'-OH RNA fragments produced by these cleavage events, we exploited the unique ligation mechanism of Escherichia coli RtcB RNA ligase to attach an oligonucleotide linker to RNAs with 5'-OH ...
Peach, Sally E. +2 more
openaire +2 more sources
Protocol for identifying differentially expressed genes using the RumBall RNA-seq analysis platform
STAR ProtocolsSummary: Here, we present a protocol for the identification of differentially expressed genes through RNA sequencing analysis. Starting with FASTQ files from public datasets, this protocol leverages RumBall within a self-contained Docker system.
Luis Augusto Eijy Nagai +2 more
doaj +1 more source
DNApi: A De Novo Adapter Prediction Algorithm for Small RNA Sequencing Data. [PDF]
PLoS ONE, 2016 With the rapid accumulation of publicly available small RNA sequencing datasets, third-party meta-analysis across many datasets is becoming increasingly powerful.
Junko Tsuji, Zhiping Weng
doaj +1 more source
PLIT: An alignment-free computational tool for identification of long non-coding RNAs in plant transcriptomic datasets [PDF]
, 2019 Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs which play a significant role in several biological processes. RNA-seq based transcriptome sequencing has been extensively used for identification of lncRNAs.
Deshpande, Sumukh +4 more
core +4 more sources
RNA Sequencing Data: Hitchhiker's Guide to Expression Analysis [PDF]
Annual Review of Biomedical Data Science, 2018 Gene expression is the fundamental level at which the results of various genetic and regulatory programs are observable. The measurement of transcriptome-wide gene expression has convincingly switched from microarrays to sequencing in a matter of years.
Van den Berge, Koen +7 more
openaire +2 more sources