Results 131 to 140 of about 2,556,924 (316)
Sequence analysis of the nicks and termini of bacteriophage T5 DNA [PDF]
, 1977 Brian P. Nichols, J E Donelson
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The Regression Analysis of Binary Sequences
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1958 Summary A sequence of 0’s and 1’s is observed and it is suspected that the chance that a particular trial is a 1 depends on the value of one or more independent variables. Tests and estimates for such situations are considered, dealing first with problems in which the independent variable is preassigned and then with independent ...
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Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
RNA-RNA interactions in the binding site of protein L24 on 23S ribosomal RNA of E. coli II. Sequence analysis of the interacting fragments [PDF]
, 1978 Alain Krol +3 more
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
DNA sequence analysis: a formula to predict electrophoretic mobilities of oligonucleotides on cellulose acetate [PDF]
, 1974 Robert A. Bambara, Ernest Jay, Ray Wü
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Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
The Suitability of Bovine‐Lens Leucine Aminopeptidase for Sequence Analysis and Limited Hydrolysis of Polypeptides [PDF]
, 1973 Bernd Wiederanders +5 more
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