Results 31 to 40 of about 2,732,974 (261)

Is the pan-genome also a pan-selectome? [v1; ref status: indexed, http://f1000r.es/Vl9wKI]

F1000Research, 2012
The comparative genomics of prokaryotes has shown the presence of conserved regions containing highly similar genes (the 'core genome') and other regions that vary in gene content (the ‘flexible’ regions).
Francisco Rodriguez-Valera, David W Ussery   +1 more
doaj   +1 more source

ANALYZING THE GENOMIC VARIATION OF MICROBIAL CELL FACTORIES IN THE ERA OF “NEW BIOTECHNOLOGY”

Computational and Structural Biotechnology Journal, 2012
The application of genome-scale technologies, both experimental and in silico, to industrial biotechnology has allowed improving the conversion of biomass-derived feedstocks to chemicals, materials and fuels through microbial fermentation. In particular,
Markus Herrgård, Gianni Panagiotou
doaj   +1 more source

Dissecting spatio‐temporal protein networks driving human heart development and related disorders

Molecular Systems Biology, 2010
Aberrant organ development is associated with a wide spectrum of disorders, from schizophrenia to congenital heart disease, but systems‐level insight into the underlying processes is very limited. Using heart morphogenesis as general model for dissecting
Kasper Lage, Kjeld Møllgård, Steven Greenway, Hiroko Wakimoto, Joshua M Gorham, Christopher T Workman, Eske Bendsen, Niclas T Hansen, Olga Rigina, Francisco S Roque, Cornelia Wiese, Vincent M Christoffels, Amy E Roberts, Leslie B Smoot, William T Pu, Patricia K Donahoe, Niels Tommerup, Søren Brunak, Christine E Seidman, Jonathan G Seidman, Lars A Larsen   +20 more
doaj   +1 more source

Analysis of the Sequence Preference of Saporin by Deep Sequencing

ACS Chemical Biology, 2022
Ribosome-inactivating proteins (RIPs) are RNA:adenosine glycosidases that inactivate eukaryotic ribosomes by depurinating the sarcin-ricin loop (SRL) in 28S rRNA. The GAGA sequence at the top of the SRL or at the top of a hairpin loop is assumed to be their target motif.
Samuel Hauf, Rachapun Rotrattanadumrong, Yohei Yokobayashi   +2 more
openaire   +2 more sources

Global phylogenetic analysis of contemporary aleutian mink disease viruses (AMDVs)

Virology Journal, 2017
Background Aleutian mink disease has major economic consequences on the mink farming industry worldwide, as it causes a disease that affects both the fur quality and the health and welfare of the mink.
P. Ryt-Hansen, E. E. Hagberg, M. Chriél, T. Struve, A. G. Pedersen, L. E. Larsen, C. K. Hjulsager   +6 more
doaj   +1 more source

Rapid Nickel-based Isolation of Extracellular Vesicles from Different Biological Fluids

Bio-Protocol, 2020
Extracellular vesicles (EVs) are membranous structures that cells massively release in extracellular fluids. EVs are cargo of cellular components such as lipids, proteins, and nucleic acids that can work as a formidable source in liquid biopsy studies ...
Michela Notarangelo, Deborah Ferrara, Cristina Potrich, Lorenzo Lunelli, Lia Vanzetti, Alessandro Provenzani, Manuela Basso, Alessandro Quattrone, Vito D'Agostino   +8 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Finding the here in where: Keatley’s Winthropping in missing persons and no-body homicide cases

Forensic Science International: Synergy
No-body homicide cases are typically difficult to investigate, owing to the lack of forensics and leads. Researchers in the fields of forensics, criminology, and psychology have attempted to provide assistance to these investigations through their ...
David A. Keatley
doaj   +1 more source

Outbreak tracking of Aleutian mink disease virus (AMDV) using partial NS1 gene sequencing

Virology Journal, 2017
Background Aleutian Mink Disease (AMD) is an infectious disease of mink (Neovison vison) and globally a major cause of economic losses in mink farming. The disease is caused by Aleutian Mink Disease Virus (AMDV) that belongs to the genus Amdoparvovirus ...
P. Ryt-Hansen, C.K. Hjulsager, E.E. Hagberg, M. Chriél, T. Struve, A.G. Pedersen, L.E. Larsen   +6 more
doaj   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source