Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells
Stem Cell Research, 2014 The shortage of molecular information on cell cycle changes along embryonic stem cell (ESC) differentiation prompts an in silico approach, which may provide a novel way to identify candidate genes or mechanisms acting in coordinating the two programs. We
Angela Re +4 more
doaj +1 more source
Is the pan-genome also a pan-selectome? [v1; ref status: indexed, http://f1000r.es/Vl9wKI]
F1000Research, 2012 The comparative genomics of prokaryotes has shown the presence of conserved regions containing highly similar genes (the 'core genome') and other regions that vary in gene content (the ‘flexible’ regions).
Francisco Rodriguez-Valera +1 more
doaj +1 more source
ANALYZING THE GENOMIC VARIATION OF MICROBIAL CELL FACTORIES IN THE ERA OF “NEW BIOTECHNOLOGY”
Computational and Structural Biotechnology Journal, 2012 The application of genome-scale technologies, both experimental and in silico, to industrial biotechnology has allowed improving the conversion of biomass-derived feedstocks to chemicals, materials and fuels through microbial fermentation. In particular,
Markus Herrgård, Gianni Panagiotou
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Dissecting spatio‐temporal protein networks driving human heart development and related disorders
Molecular Systems Biology, 2010 Aberrant organ development is associated with a wide spectrum of disorders, from schizophrenia to congenital heart disease, but systems‐level insight into the underlying processes is very limited. Using heart morphogenesis as general model for dissecting
Kasper Lage +20 more
doaj +1 more source
Combining Sequence Analysis and Hidden Markov Models in the Analysis of Complex Life Sequence Data
, 2018 Life course data often consists of multiple parallel sequences, one for each life domain of interest. Multichannel sequence analysis has been used for computing pairwise dissimilarities and finding clusters in this type of multichannel (or ...
Satu Helske +8 more
core +1 more source
BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction [PDF]
, 2009 A novel discrete mathematical approach is proposed as an additional tool for molecular systematics which does not require prior statistical assumptions concerning the evolutionary process.
Ittzés, Péter +4 more
core +1 more source
Rapid Nickel-based Isolation of Extracellular Vesicles from Different Biological Fluids
Bio-Protocol, 2020 Extracellular vesicles (EVs) are membranous structures that cells massively release in extracellular fluids. EVs are cargo of cellular components such as lipids, proteins, and nucleic acids that can work as a formidable source in liquid biopsy studies ...
Michela Notarangelo +8 more
doaj +1 more source
Global phylogenetic analysis of contemporary aleutian mink disease viruses (AMDVs)
Virology Journal, 2017 Background Aleutian mink disease has major economic consequences on the mink farming industry worldwide, as it causes a disease that affects both the fur quality and the health and welfare of the mink.
P. Ryt-Hansen +6 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Finding the here in where: Keatley’s Winthropping in missing persons and no-body homicide cases
Forensic Science International: SynergyNo-body homicide cases are typically difficult to investigate, owing to the lack of forensics and leads. Researchers in the fields of forensics, criminology, and psychology have attempted to provide assistance to these investigations through their ...
David A. Keatley
doaj +1 more source