Results 61 to 70 of about 31,098,092 (376)

The EVcouplings Python framework for coevolutionary sequence analysis

bioRxiv, 2018
Summary Coevolutionary sequence analysis has become a commonly used technique for de novo prediction of the structure and function of proteins, RNA, and protein complexes.
Thomas A. Hopf, Anna G. Green, B. Schubert, Sophia Mersmann, Charlotta P I Schärfe, John Ingraham, Agnes Toth-Petroczy, Kelly P. Brock, Adam J. Riesselman, P. Palmedo, C. Kang, R. Sheridan, Eli J. Draizen, Christian Dallago, C. Sander, D. Marks   +15 more
semanticscholar   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Finding the here in where: Keatley’s Winthropping in missing persons and no-body homicide cases

Forensic Science International: Synergy
No-body homicide cases are typically difficult to investigate, owing to the lack of forensics and leads. Researchers in the fields of forensics, criminology, and psychology have attempted to provide assistance to these investigations through their ...
David A. Keatley
doaj   +1 more source

Outbreak tracking of Aleutian mink disease virus (AMDV) using partial NS1 gene sequencing

Virology Journal, 2017
Background Aleutian Mink Disease (AMD) is an infectious disease of mink (Neovison vison) and globally a major cause of economic losses in mink farming. The disease is caused by Aleutian Mink Disease Virus (AMDV) that belongs to the genus Amdoparvovirus ...
P. Ryt-Hansen, C.K. Hjulsager, E.E. Hagberg, M. Chriél, T. Struve, A.G. Pedersen, L.E. Larsen   +6 more
doaj   +1 more source

RSAT 2018: regulatory sequence analysis tools 20th anniversary

Nucleic Acids Res., 2018
RSAT (Regulatory Sequence Analysis Tools) is a suite of modular tools for the detection and the analysis of cis-regulatory elements in genome sequences. Its main applications are (i) motif discovery, including from genome-wide datasets like ChIP-seq/ATAC-
N. Nguyen, B. Contreras-Moreira, J. Castro-Mondragón, Walter Santana-Garcia, Raul Ossio, C. D. Robles-Espinoza, Mathieu Bahin, Samuel Collombet, P. Vincens, D. Thieffry, J. Helden, A. Medina-Rivera, Morgane Thomas-Chollier   +12 more
semanticscholar   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Epstein–Barr virus (Herpesviridae: Gammaherpesvirinae: Lymphocryptovirus: Human gammaherpesvirus 4) in Kalmyks and Slavs living in Russia: virus types, LMP1 oncogene variants, and malignancies

Вопросы вирусологии, 2022
Introduction. The discovery of the Epstein-Barr virus types (Herpesviridae: Gammaherpesvirinae: Lymphocryptovirus: Human gammaherpesvirus 4) (EBV) EBV-1 and EBV-2, which have different transforming abilities in vitro, stimulated the study of their ...
Vladimir E. Gurtsevitch, Alexandra K. Lubenskaya, Natalia B. Senyuta, Tatiana E. Dushenkina, Ksenia V. Smirnova   +4 more
doaj   +1 more source

Complete sequence of the genome of the human isolate of Andes virus CHI-7913: comparative sequence and protein structure analysis [PDF]

, 2003
Indexación: ScieloWe report here the complete genomic sequence of the Chilean human isolate of Andes virus CHI-7913. The S, M, and L genome segment sequences of this isolate are 1,802, 3,641 and 6,466 bases in length, with an overall GC content of 38.7%.
Fernández, Jorge, Galeno, Héctor, Martínez, Rodrigo, Mora, Judith, Müller, Ilse, Ramírez, Eugenio, Rosemblatt, Mario, Tischler, Nicole D., Valenzuela, Pablo D.T., Villagra, Eliecer   +9 more
core   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

FluKB: A Knowledge-Based System for Influenza Vaccine Target Discovery and Analysis of the Immunological Properties of Influenza Viruses

Journal of Immunology Research, 2015
FluKB is a knowledge-based system focusing on data and analytical tools for influenza vaccine discovery. The main goal of FluKB is to provide access to curated influenza sequence and epitope data and enhance the analysis of influenza sequence diversity ...
Christian Simon, Ulrich J. Kudahl, Jing Sun, Lars Rønn Olsen, Guang Lan Zhang, Ellis L. Reinherz, Vladimir Brusic   +6 more
doaj   +1 more source