Results 71 to 80 of about 29,786,749 (389)

Genome-Guided Analysis of Seven Weed Species Reveals Conserved Sequence and Structural Features of Key Gene Targets for Herbicide Development

Frontiers in Plant Science, 2022
Herbicides are commonly deployed as the front-line treatment to control infestations of weeds in native ecosystems and among crop plants in agriculture. However, the prevalence of herbicide resistance in many species is a major global challenge.
Sarah Shah, Sarah Shah, Thierry Lonhienne, Cody-Ellen Murray, Yibi Chen, Yibi Chen, Katherine E. Dougan, Katherine E. Dougan, Yu Shang Low, Craig M. Williams, Gerhard Schenk, Gerhard Schenk, Gerhard Schenk, Gimme H. Walter, Luke W. Guddat, Cheong Xin Chan, Cheong Xin Chan   +16 more
doaj   +1 more source

Model selection and sensitivity analysis for sequence pattern models

, 2008
In this article we propose a maximal a posteriori (MAP) criterion for model selection in the motif discovery problem and investigate conditions under which the MAP asymptotically gives a correct prediction of model size. We also investigate robustness of
Gupta, Mayetri
core   +1 more source

Interpreting the Ionization Sequence in Star-Forming Galaxy Emission-Line Spectra [PDF]

, 2016
High ionization star forming (SF) galaxies are easily identified with strong emission line techniques such as the BPT diagram, and form an obvious ionization sequence on such diagrams.
Allen, James T., Baldwin, Jack A., Crider, Anthony, Ferland, Gary J., Hewett, Paul C., Meskhidze, Helen, Richardson, Chris T.   +6 more
core   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

FluKB: A Knowledge-Based System for Influenza Vaccine Target Discovery and Analysis of the Immunological Properties of Influenza Viruses

Journal of Immunology Research, 2015
FluKB is a knowledge-based system focusing on data and analytical tools for influenza vaccine discovery. The main goal of FluKB is to provide access to curated influenza sequence and epitope data and enhance the analysis of influenza sequence diversity ...
Christian Simon, Ulrich J. Kudahl, Jing Sun, Lars Rønn Olsen, Guang Lan Zhang, Ellis L. Reinherz, Vladimir Brusic   +6 more
doaj   +1 more source

Identification of Known and Novel Recurrent Viral Sequences in Data from Multiple Patients and Multiple Cancers

Viruses, 2016
Virus discovery from high throughput sequencing data often follows a bottom-up approach where taxonomic annotation takes place prior to association to disease.
Jens Friis-Nielsen, Kristín Rós Kjartansdóttir, Sarah Mollerup, Maria Asplund, Tobias Mourier, Randi Holm Jensen, Thomas Arn Hansen, Alba Rey-Iglesia, Stine Raith Richter, Ida Broman Nielsen, David E. Alquezar-Planas, Pernille V. S. Olsen, Lasse Vinner, Helena Fridholm, Lars Peter Nielsen, Eske Willerslev, Thomas Sicheritz-Pontén, Ole Lund, Anders Johannes Hansen, Jose M. G. Izarzugaza, Søren Brunak   +20 more
doaj   +1 more source

sraX: A Novel Comprehensive Resistome Analysis Tool

Frontiers in Microbiology, 2020
The accurate identification of the assortment of antibiotic resistance genes within a collection of genomes enables the discernment of intricate antimicrobial resistance (AMR) patterns while depicting the diversity of resistome profiles of the analyzed ...
Leonardo G. Panunzi, Leonardo G. Panunzi
doaj   +1 more source

Monocyte Transcriptional Responses to Mycobacterium tuberculosis Associate with Resistance to Tuberculin Skin Test and Interferon Gamma Release Assay Conversion

mSphere, 2022
Heavy exposure to Mycobacterium tuberculosis, the etiologic agent of tuberculosis (TB) and among the top infectious killers worldwide, results in infection that is cleared, contained, or progresses to disease.
Jason D. Simmons, Kimberly A. Dill-McFarland, Catherine M. Stein, Phu T. Van, Violet Chihota, Thobani Ntshiqa, Pholo Maenetje, Glenna J. Peterson, Penelope Benchek, Mary Nsereko, Kavindhran Velen, Katherine L. Fielding, Alison D. Grant, Raphael Gottardo, Harriet Mayanja-Kizza, Robert S. Wallis, Gavin Churchyard, W. Henry Boom, Thomas R. Hawn   +18 more
doaj   +1 more source

Sequence analysis of the cupin gene family in Synechocystis PCC6803 [PDF]

, 1998
The recently described cupin superfamily of proteins includes the germin and germinlike proteins, of which the cereal oxalate oxidase is the best characterized.
DUNWELL J.M., GANE P.J., JIM M. DUNWELL, LANE B.G., LEHEL C, MEHTA   +5 more
core   +1 more source

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry.

Proceedings of the National Academy of Sciences of the United States of America, 2004
Peptide sequence analysis using a combination of gas-phase ion/ion chemistry and tandem mass spectrometry (MS/MS) is demonstrated. Singly charged anthracene anions transfer an electron to multiply protonated peptides in a radio frequency quadrupole ...
J. Syka, J. Coon, M. Schroeder, J. Shabanowitz, D. Hunt   +4 more
semanticscholar   +1 more source