Results 71 to 80 of about 30,598,754 (388)

Identification of Known and Novel Recurrent Viral Sequences in Data from Multiple Patients and Multiple Cancers

open access: yesViruses, 2016
Virus discovery from high throughput sequencing data often follows a bottom-up approach where taxonomic annotation takes place prior to association to disease.
Jens Friis-Nielsen   +20 more
doaj   +1 more source

Protein sectors: statistical coupling analysis versus conservation

open access: yes, 2014
Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed "sectors".
Colwell, Lucy J.   +2 more
core   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

The SH2 Domain Interaction Landscape

open access: yesCell Reports, 2013
Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines. Each domain displays a distinct preference for the sequence context of the phosphorylated residue.
Michele Tinti   +18 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations

open access: yesLeukemia, 2017
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia : updated ERIC ...
Richard Rosenquist   +14 more
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis

open access: yesnpj Biofilms and Microbiomes, 2017
Psoriasis: investigating microbial diversity Analysing microbial populations on the skin provides an insight into the diversity of microbes associated with psoriasis.
Adrian Tett   +13 more
doaj   +1 more source

Analysis of CDR3 Sequences from T-Cell Receptor β in Acute Respiratory Distress Syndrome

open access: yesBiomolecules, 2023
Acute Respiratory Distress Syndrome (ARDS) is an illness that typically develops in people who are significantly ill or have serious injuries. ARDS is characterized by fluid build-up that occurs in the alveoli. T-cells are implicated as playing a role in
Sara Hey   +8 more
doaj   +1 more source

Fast Sequence Component Analysis for Attack Detection in Synchrophasor Networks [PDF]

open access: yes, 2015
Modern power systems have begun integrating synchrophasor technologies into part of daily operations. Given the amount of solutions offered and the maturity rate of application development it is not a matter of "if" but a matter of "when" in regards to ...
Barella, Richard   +6 more
core   +2 more sources

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