Results 231 to 240 of about 5,890,604 (383)

LDBT instead of DBTL: combining machine learning and rapid cell-free testing. [PDF]

Nat Commun
Clark-ElSayed A, Harrison IM, Olsen ML, Lazar JT, Jewett MC, Ellington AD.   +5 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Rapid on-site universal vertebrate species identification via multi-barcode nanopore sequencing. [PDF]

PLoS One
Patterson EC, Morrison-Lanjouw S, Jobling MA, Wetton JH.   +3 more
europepmc   +1 more source

The Complete Genome Sequence of Escherichia coli DH10B: Insights into the Biology of a Laboratory Workhorse

, 2008
Tim Durfee, Richard G. Nelson, Schuyler Baldwin, Guy Plunkett, Valerie Burland, Bob Mau, Joseph F. Petrosino, Xiang Qin, Donna M. Muzny, Mulu Ayele, Richard A. Gibbs, Bálint Csörgő, György Pósfai, George M. Weinstock, Frederick R. Blattner   +14 more
openalex   +1 more source

Multilocus sequence analysis, a rapid and accurate identification tool for taxonomic classification, evolutionary relationship and population biology of the genus Shewanella [PDF]

, 2019
Yujie Fang, Yonglu Wang, Zongdong Liu, Hang Dai, Hongyan Cai, Zhenpeng Li, Zong‐Jun Du, Xin Wang, Huaiqi Jing, Qiang Wei, Biao Kan, Duochun Wang   +11 more
openalex   +1 more source

Overview of MicroRNA Biology

Seminars in liver disease (Print), 2015
Ashley M. Mohr, J. Mott
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

OneProt: Towards multi-modal protein foundation models via latent space alignment of sequence, structure, binding sites and text encoders. [PDF]

PLoS Comput Biol
Flöge K, Udayakumar S, Sommer J, Piraud M, Kesselheim S, Fortuin V, Günnemann S, van der Weg KJ, Gohlke H, Merdivan E, Bazarova A.   +10 more
europepmc   +1 more source

Gaps as characters in sequence-based phylogenetic analyses.

Systematic Biology, 2000
Mark P. Simmons, H. Ochoterena
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source