ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
SVNeoPP: A Workflow for Structural-Variant-Derived Neoantigen Prediction and Prioritization Using Multi-Omics Data. [PDF]
An W, Tan X, Liu Z, Zou L, Lu M, Xie L.
europepmc +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Draft genome sequence of <i>Escherichia coli</i> LA3 isolated from influent wastewater discharge of a tertiary-level hospital in Laguna, Philippines. [PDF]
Padon SDM +8 more
europepmc +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Author Correction: Genotyping sequence-resolved copy number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes. [PDF]
Ma W, Chaisson MJP.
europepmc +1 more source
Isolation and Genome Annotation of TicTac, an EK1 Cluster Bacteriophage with Podovirus Morphology. [PDF]
Allgood M +17 more
europepmc +1 more source
MinION Sequencer Demonstrates Strong DNA Sequencing Accuracy and Identity. [PDF]
Gallagher A, Illendula P, Pu R.
europepmc +1 more source

