Results 231 to 240 of about 4,078,643 (261)

Development of Gap-Recombinase Polymerase Amplification Combined with CRISPR-Cas12a (Gap-RPA/CRISPR-Cas12a) for Rapid Screening of α⁰-Thalassemia Southeast Asian (--^SEA) Deletion and Thai (--^THAI) Deletion. [PDF]

Biology (Basel)
Changtor P, Muangpa S, Yimtragool N.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

FoldaVirus, a knowledge-based icosahedral capsid prediction tool using AlphaFold. [PDF]

Proc Natl Acad Sci U S A
Rojas Labra O, Montoya-Munoz DS, Santoyo-Rivera N, McDonald J, Montiel-Garcia D, Case DA, Reddy VS.   +6 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The distribution of fitness effects of nonsynonymous mutations varies phylogenetically across animals. [PDF]

PLoS Biol
Lin M, Chakraborty S, Amorim CEG, Nigenda-Morales SF, Beichman AC, Nuñez-Valencia PG, Mah JC, Robinson JA, Kyriazis CC, Huber CD, Webb AE, Kocher SD, Archer FI, Moreno-Estrada A, Wayne RK, Lohmueller KE.   +15 more
europepmc   +1 more source

Transcriptional architecture of African swine fever virus. [PDF]

PLoS Pathog
Wang G, Li P, He X, Cao H, H Ghonaim A, Ruan S, Yu X, Zhou J, Zhu H, Zhang M, Jongkaewwattana A, Peng G, He Q, Li W.   +13 more
europepmc   +1 more source

Demystifying Computational Biology: A Scalable Drug Discovery Framework for Medical Curricula. [PDF]

Cureus
Campbell CO.
europepmc   +1 more source

A Chromosome-scale Assembly for the Genome of Southern Corn Rootworm, Diabrotica Undecimpunctata. [PDF]

Genome Biol Evol
Coates BS, Geib SM, Tembrock LR, Vélez A, Poelchau M, Childers C, Childers A, Cooksey A, Hackett K, Sim SB.   +9 more
europepmc   +1 more source

Multilocus DNA Barcoding Resolves Area-Based Genetic Variation in Freshwater Shrimps (<i>Macrobrachium</i> sp. and <i>Caridina</i> sp.) from Saline and Non-Saline Habitats in Northeastern Thailand. [PDF]

Biology (Basel)
Saengprajak J, Pakdeenarong N.
europepmc   +1 more source