Results 241 to 250 of about 5,758,485 (356)

Structural Biology in the AlphaFold Era: How Far Is Artificial Intelligence from Deciphering the Protein Folding Code? [PDF]

Biomolecules
Balasco N, Esposito L, Vitagliano L.
europepmc   +1 more source

Marine Organism Cell Biology and Regulatory Sequence Discoveryin Comparative Functional Genomics [PDF]

, 2004
David W. Barnes, Carolyn Mattingly, Angela Parton, Lori Dowell, Christopher J. Bayne, John N. Forrest   +5 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Rapidly obtaining genome sequence of Severe Fever with Thrombocytopenia Syndrome virus directly from clinical serum specimen using long amplicon based nanopore sequencing workflow. [PDF]

PLoS One
Tian T, Wen Y, Gao L, Liu T, Huang X, Li C, Du S, Li H, Guo M, Li J, Wang S, Li D, Li A, Liang M.   +13 more
europepmc   +1 more source

A chromosome-based draft sequence of the hexaploid bread wheat (Triticum aestivum) genome

Science, 2014
D. Edwards, J. Batley
semanticscholar   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Protocol for mitochondrial DNA isolation from Macrobrachium rosenbergii and Penaeus monodon using differential centrifugation

STAR Protocols
Summary: The mitochondrial genome (mitogenome) is a vital tool in molecular phylogenetics, evolutionary biology, and population genetics. Here, we present a protocol for extracting mitochondrial DNA from shrimp (Macrobrachium rosenbergii) and prawn ...
Dipta Chandra Pal, Muhammad Manjurul Karim   +1 more
doaj  

Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering. [PDF]

RNA
De S, Zhou M, Brown ZP, Burton-Smith RN, Hashem Y, Pestova TV, Hellen CUT, Frank J.   +7 more
europepmc   +1 more source

First Insights into the Evolution of Streptococcus uberis : a Multilocus Sequence Typing Scheme That Enables Investigation of Its Population Biology [PDF]

, 2006
Tracey J. Coffey, Gillian D. Pullinger, Rachel Urwin, Keith A. Jolley, Stephen M. Wilson, Martin Maiden, James A. Leigh   +6 more
openalex   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source