Results 91 to 100 of about 1,667,563 (261)

FlatProt: 2D visualization eases protein structure comparison

open access: yesBMC Bioinformatics
Background Understanding and comparing three-dimensional (3D) structures of proteins can advance bioinformatics, molecular biology, and drug discovery.
Tobias Olenyi   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Genomic sequencing and analyses of HearMNPV—a new Multinucleocapsid nucleopolyhedrovirus isolated from Helicoverpa armigera

open access: yesVirology Journal, 2012
Background HearMNPV, a nucleopolyhedrovirus (NPV), which infects the cotton bollworm, Helicoverpa armigera, comprises multiple rod-shaped nucleocapsids in virion(as detected by electron microscopy).
Tang Ping   +6 more
doaj   +1 more source

Secure and Efficient Outsourcing of Sequence Comparisons

open access: yes, 2012
We treat the problem of secure outsourcing of sequence comparisons by a client to remote servers, which given two strings λ and μ of respective lengths n and m, consists of finding a minimum-cost sequence of insertions, deletions, and substitutions (also called an edit script) that transform λ into μ. In our setting a client owns λ and μ and outsources
Marina Blanton   +3 more
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Comparative analysis of the complete plastomes of three Cardamine in Korea and phylogenomic study of Cardamine (Brassicaceae, Brassicales)

open access: yesJournal of Asia-Pacific Biodiversity
Plastome studies of Cardamine, which is widely distributed in Northeast Asia, are essential for phylogenetic and evolutionary research. In this study, we report the complete plastome sequences of three Cardamine species; C. komarovii, C. leucantha, and C.
Sangjin Jo   +4 more
doaj   +1 more source

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