Results 101 to 110 of about 4,146,099 (286)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Comparison of sequence-dependent tiling array normalization approaches
BMC Bioinformatics, 2009 Background The detection of enriched DNA or RNA fragments by tiling microarrays has become more and more popular. These microarrays contain a high number of small probes covering genomic loci.
Vingron Martin, Chung Ho-Ryun
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Structure, Organization, and Expression of the lct Gene for Lacticin 481, a Novel Lantibiotic Produced by Lactococcus lactis [PDF]
, 1993 The structural gene for the lactococcal lantibiotic lacticin 481 (lct) has been identified and cloned using a degenerated 20-mer DNA oligonucleotide based on the amino-terminal 7 amino acid residues of the purified protein.
Desmazeaud, Michel J., +4 more
core +1 more source
Comparison of Sobol’ sequences in financial applications [PDF]
Monte Carlo Methods and Applications, 2019 Abstract Sobol’ sequences are widely used for quasi-Monte Carlo methods that arise in financial applications. Sobol’ sequences have parameter values called direction numbers, which are freely chosen by the user, so there are several implementations of Sobol’ sequence generators. The aim of this paper is to provide a comparative study of (
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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Geometric Aspects of Biological Sequence Comparison
Journal of Computational Biology, 2009 Abstract We introduce a geometric framework suitable for studying the relationships among biological sequences. In contrast to previous works, our formulation allows asymmetric distances (quasi-metrics), originating from uneven weighting of strings, which may induce non-trivial partial orders on sets of biosequences.
Aleksandar Stojmirovic, Yi-Kuo Yu
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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E-SC: Collusion-Resistant Secure Outsourcing of Sequence Comparison Algorithm
IEEE Access, 2018 The sequence comparison of large-scale string-typed data is fundamental in computer science and other computational disciplines. Its development has been promoted into an emerging outsourcing service by the almost unlimited powerful computing and storage
Xiaofei Wang, Yuqing Zhang
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Quality of Algorithms for Sequence Comparison [PDF]
, 2011 Pair-wise sequence alignment is the basic method of comparative analysis of proteins and nucleic acids. Studying the results of the alignment one has to consider two questions: (1) did the program find all the interesting similarities ("sensitivity") and (2) are all the found similarities interesting ("selectivity").
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